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  • 21 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Cullin Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Proteins Medicine & Life Sciences
Growth Medicine & Life Sciences

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Grants 2004 2021

Research Output 1987 2018

2 Citations

High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction

Zhou, H., Zhou, W., Zhou, B., Liu, L., Chern, T. R., Chinnaswamy, K., Lu, J., Bernard, D., Yang, C. Y., Li, S., Wang, M., Stuckey, J., Sun, Y. & Wang, S. Mar 8 2018 In : Journal of medicinal chemistry. 61, 5, p. 1934-1950 17 p.

Research output: Contribution to journalArticle

Cullin Proteins
2 Citations

Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes

Zhao, Y., Tan, M., Liu, X., Xiong, X. & Sun, Y. Feb 1 2018 In : Cell Death and Disease. 9, 2, 145

Research output: Contribution to journalArticle

Ribosomal Proteins
Radiation Tolerance
DNA Damage
Ubiquitin-Protein Ligases

Protein neddylation and its alterations in human cancers for targeted therapy

Zhou, L., Zhang, W., Sun, Y. & Jia, L. Apr 1 2018 In : Cellular Signalling. 44, p. 92-102 11 p.

Research output: Contribution to journalReview article

Cullin Proteins
Biochemical Phenomena
4 Citations

A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation

Zhou, H., Lu, J., Liu, L., Bernard, D., Yang, C. Y., Fernandez-Salas, E., Chinnaswamy, K., Layton, S., Stuckey, J., Yu, Q., Zhou, W., Pan, Z., Sun, Y. & Wang, S. Dec 1 2017 In : Nature Communications. 8, 1, 1150

Research output: Contribution to journalArticle

Cullin Proteins
2 Citations

Inhibition of Neddylation Modification Sensitizes Pancreatic Cancer Cells to Gemcitabine

Li, H., Zhou, W., Li, L., Wu, J., Liu, X., Zhao, L., Jia, L. & Sun, Y. Jun 1 2017 In : Neoplasia (United States). 19, 6, p. 509-518 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Apoptosis Regulatory Proteins