Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 12 Similar Profiles
Neoplasms Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Growth Medicine & Life Sciences
Cullin Proteins Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2004 2021

Research Output 1987 2017

A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation

Zhou, H., Lu, J., Liu, L., Bernard, D., Yang, C. Y., Fernandez-Salas, E., Chinnaswamy, K., Layton, S., Stuckey, J., Yu, Q., Zhou, W., Pan, Z., Sun, Y. & Wang, S. Dec 1 2017 In : Nature Communications. 8, 1, 1150

Research output: Research - peer-reviewArticle

inhibitors
proteins
molecules
interactions
Cullin Proteins

Inhibition of Neddylation Modification Sensitizes Pancreatic Cancer Cells to Gemcitabine

Li, H., Zhou, W., Li, L., Wu, J., Liu, X., Zhao, L., Jia, L. & Sun, Y. Jun 1 2017 In : Neoplasia (United States). 19, 6, p. 509-518 10 p.

Research output: Research - peer-reviewArticle

gemcitabine
Pancreatic Neoplasms
Adenocarcinoma
((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate
Survival
2 Citations

Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage

Zhou, W., Xu, J., Li, H., Xu, M., Chen, Z. J., Wei, W., Pan, Z. & Sun, Y. Feb 15 2017 In : Clinical Cancer Research. 23, 4, p. 1104-1116 13 p.

Research output: Research - peer-reviewArticle

Cullin Proteins
Ligases
Lung Neoplasms
Survival
Neoplasms

Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKI

Li, H., Xiao, N., Wang, Y., Wang, R., Chen, Y., Pan, W., Liu, D., Li, S., Sun, J., Zhang, K., Sun, Y. & Ge, X. Oct 12 2017 In : Oncogene. 36, 41, p. 5668-5680 13 p.

Research output: Research - peer-reviewArticle

Ubiquitination
Cell Movement
Lung Neoplasms
Growth
Phosphotransferases
1 Citations

The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor

Xu, J., Zhou, W., Yang, F., Chen, G., Li, H., Zhao, Y., Liu, P., Li, H., Tan, M., Xiong, X. & Sun, Y. Jan 16 2017 In : Nature Communications. 8, 14002

Research output: Research - peer-reviewArticle

suppressors
lungs
tumors
cancer
beta-Transducin Repeat-Containing Proteins