Tomasz Cierpicki

  • 2207 Citations
  • 27 Scopus h-Index
19992021

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Proteins Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Myeloid-Lymphoid Leukemia Protein Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences

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Grants 2011 2021

Research Output 1999 2017

  • 2207 Citations
  • 27 Scopus h-Index
  • 67 Article
  • 4 Review article
  • 1 Letter

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Svoboda, L. K., Bailey, N., Van Noord, R. A., Krook, M. A., Harris, A., Cramer, C., Jasman, B., Patel, R. M., Thomas, D., Borkin, D., Cierpicki, T., Grembecka, J. & Lawlor, E. R. 2017 In : Oncotarget. 8, 1, p. 458-471 14 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Proteins
Transcriptional Activation
Neoplasms
Leukemia

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

Gray, F., Cho, H. J., Shukla, S., He, S., Harris, A., Boytsov, B., Jaremko, A., Jaremko, M., Demeler, B., Lawlor, E. R., Grembecka, J. & Cierpicki, T. Nov 9 2016 In : Nature Communications. 7, 13343

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Proteins
Oligomerization
Ubiquitin
Ubiquitination

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C

Carpenter, C., Sorenson, R. J., Jin, Y., Klossowski, S., Cierpicki, T., Gnegy, M. & Showalter, H. D. 2016 In : Bioorganic and Medicinal Chemistry. 24, 21, p. 5495-5504 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Protein Kinase C
Amphetamine-Related Disorders
Inhibition (Psychology)
Acrylonitrile
1 Citations

H3K36 methyltransferases as cancer drug targets: Rationale and perspectives for inhibitor development

Rogawski, D. S., Grembecka, J. & Cierpicki, T. Sep 1 2016 In : Future Medicinal Chemistry. 8, 13, p. 1589-1607 19 p.

Research output: Contribution to journalReview article

Methyltransferases
Genes
Neoplasms
Alternative Splicing
Epigenomics
1 Citations

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)

Borkin, D., Pollock, J., Kempinska, K., Purohit, T., Li, X., Wen, B., Zhao, T., Miao, H., Shukla, S., He, M., Sun, D., Cierpicki, T. & Grembecka, J. Feb 11 2016 In : Journal of Medicinal Chemistry. 59, 3, p. 892-913 22 p.

Research output: Contribution to journalArticle

Leukemia
Proteins
Lead
Myeloid-Lymphoid Leukemia Protein
Biphenotypic Acute Leukemia