Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Cerebellar Ataxia Chemical Compounds
Hydroxymethylglutaryl-CoA Reductase Inhibitors Medicine & Life Sciences
Pyrroles Medicine & Life Sciences
Genes Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Acids Medicine & Life Sciences
Cyclic AMP Receptor Protein Chemical Compounds
Transcription Chemical Compounds

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Grants 1997 2020

Research Output 1984 2017

  • 1949 Citations
  • 25 Scopus h-Index
  • 78 Article
  • 2 Review article
  • 1 Comment/debate
4 Citations

Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence

Zheng, H., Colvin, C. J., Johnson, B. K., Kirchhoff, P. D., Wilson, M., Jorgensen-Muga, K., Larsen, S. D. & Abramovitch, R. B. Feb 1 2017 In : Nature Chemical Biology. 13, 2, p. 218-225 8 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Heme
Phosphotransferases
Small Molecule Libraries
Regulon
1 Citations

Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis

Yu-Wai-Man, C., Spencer-Dene, B., Lee, R. M. H., Hutchings, K., Lisabeth, E. M., Treisman, R., Bailly, M., Larsen, S. D., Neubig, R. R. & Khaw, P. T. Dec 1 2017 In : Scientific Reports. 7, 1, 518

Research output: Contribution to journalArticle

Serum Response Factor
Cicatrix
Fibrosis
Transcription Factors
Genes

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma

Hutchings, K. M., Lisabeth, E. M., Rajeswaran, W., Wilson, M. W., Sorenson, R. J., Campbell, P. L., Ruth, J. H., Amin, A., Tsou, P. S., Leipprandt, J. R., Olson, S. R., Wen, B., Zhao, T., Sun, D., Khanna, D., Fox, D. A., Neubig, R. R. & Larsen, S. D. Apr 15 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 8, p. 1744-1749 6 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Fibrosis
Pharmacokinetics
Forearm
Pharmaceutical Chemistry

Pharmacological inhibition of myocardin-related transcription factor pathway blocks lung metastases of RhoC-Overexpressing melanoma

Haak, A. J., Appleton, K. M., Lisabeth, E. M., Misek, S. A., Ji, Y., Wade, S. M., Bell, J. L., Rockwell, C. E., Airik, M., Krook, M. A., Larsen, S. D., Verhaegen, M., Lawlor, E. R. & Neubig, R. R. Jan 1 2017 In : Molecular Cancer Therapeutics. 16, 1, p. 193-204 12 p.

Research output: Contribution to journalArticle

Melanoma
Transcription Factors
Pharmacology
Neoplasm Metastasis
Lung
2 Citations

Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine

Waldschmidt, H. V., Homan, K. T., Cato, M. C., Cruz-Rodríguez, O., Cannavo, A., Wilson, M. W., Song, J., Cheung, J. Y., Koch, W. J., Tesmer, J. J. G. & Larsen, S. D. Apr 13 2017 In : Journal of Medicinal Chemistry. 60, 7, p. 3052-3069 18 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 2
Paroxetine
G-Protein-Coupled Receptor Kinases
Heterotrimeric GTP-Binding Proteins
Drug Design