Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Hydroxymethylglutaryl-CoA Reductase Inhibitors Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Genes Medicine & Life Sciences
Pyrroles Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Molecules Chemical Compounds
Transcription Chemical Compounds
Pharmaceutical Preparations Medicine & Life Sciences

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Grants 1997 2020

Research Output 1984 2017

  • 1988 Citations
  • 25 Scopus h-Index
  • 79 Article
  • 2 Review article
  • 1 Comment/debate
4 Citations

Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence

Zheng, H., Colvin, C. J., Johnson, B. K., Kirchhoff, P. D., Wilson, M., Jorgensen-Muga, K., Larsen, S. D. & Abramovitch, R. B. Feb 1 2017 In : Nature Chemical Biology. 13, 2, p. 218-225 8 p.

Research output: Research - peer-reviewArticle

Mycobacterium tuberculosis
Heme
artemisinine
Phosphotransferases
Small Molecule Libraries
1 Citations

Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis

Yu-Wai-Man, C., Spencer-Dene, B., Lee, R. M. H., Hutchings, K., Lisabeth, E. M., Treisman, R., Bailly, M., Larsen, S. D., Neubig, R. R. & Khaw, P. T. Dec 1 2017 In : Scientific Reports. 7, 1, 518

Research output: Research - peer-reviewArticle

Serum Response Factor
Cicatrix
Fibrosis
Transcription Factors
myocardin

Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease

Beck, M. W., Derrick, J. S., Suh, J. M., Kim, M., Korshavn, K. J., Kerr, R. A., Cho, W. J., Larsen, S. D., Ruotolo, B. T., Ramamoorthy, A. & Lim, M. H. 2017 (Accepted/In press) In : ChemMedChem.

Research output: Research - peer-reviewArticle

Alzheimer Disease
Metals
Molecules
Amyloid
Free Radicals

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma

Hutchings, K. M., Lisabeth, E. M., Rajeswaran, W., Wilson, M. W., Sorenson, R. J., Campbell, P. L., Ruth, J. H., Amin, A., Tsou, P. S., Leipprandt, J. R., Olson, S. R., Wen, B., Zhao, T., Sun, D., Khanna, D., Fox, D. A., Neubig, R. R. & Larsen, S. D. 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 8, p. 1744-1749 6 p.

Research output: Research - peer-reviewArticle

Pharmacokinetics
Bleomycin
Transcription
Animals
Solubility

Pharmacological inhibition of myocardin-related transcription factor pathway blocks lung metastases of RhoC-Overexpressing melanoma

Haak, A. J., Appleton, K. M., Lisabeth, E. M., Misek, S. A., Ji, Y., Wade, S. M., Bell, J. L., Rockwell, C. E., Airik, M., Krook, M. A., Larsen, S. D., Verhaegen, M., Lawlor, E. R. & Neubig, R. R. Jan 1 2017 In : Molecular Cancer Therapeutics. 16, 1, p. 193-204 12 p.

Research output: Research - peer-reviewArticle

Melanoma
Transcription Factors
Pharmacology
Neoplasm Metastasis
Lung