Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Hydroxymethylglutaryl-CoA Reductase Inhibitors Medicine & Life Sciences
Genes Medicine & Life Sciences
Pyrroles Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Acids Medicine & Life Sciences
Serum Response Factor Medicine & Life Sciences
Alphavirus Medicine & Life Sciences
Hypercholesterolemia Medicine & Life Sciences

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Grants 2009 2020

Research Output 1984 2017

  • 1772 Citations
  • 23 Scopus h-Index
  • 75 Article
  • 2 Review article
  • 1 Comment/debate

Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis

Yu-Wai-Man, C., Spencer-Dene, B., Lee, R. M. H., Hutchings, K., Lisabeth, E. M., Treisman, R., Bailly, M., Larsen, S. D., Neubig, R. R. & Khaw, P. T. Dec 1 2017 In : Scientific Reports. 7, 1, 518

Research output: Contribution to journalArticle

Serum Response Factor
Cicatrix
Fibrosis
Transcription Factors
Genes

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma

Hutchings, K. M., Lisabeth, E. M., Rajeswaran, W., Wilson, M. W., Sorenson, R. J., Campbell, P. L., Ruth, J. H., Amin, A., Tsou, P. S., Leipprandt, J. R., Olson, S. R., Wen, B., Zhao, T., Sun, D., Khanna, D., Fox, D. A., Neubig, R. R. & Larsen, S. D. Apr 15 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 8, p. 1744-1749 6 p.

Research output: Contribution to journalArticle

Fibrosis
Pharmacokinetics
Pharmaceutical Chemistry
Bleomycin
Solubility

Pharmacological inhibition of myocardin-related transcription factor pathway blocks lung metastases of RhoC-Overexpressing melanoma

Haak, A. J., Appleton, K. M., Lisabeth, E. M., Misek, S. A., Ji, Y., Wade, S. M., Bell, J. L., Rockwell, C. E., Airik, M., Krook, M. A., Larsen, S. D., Verhaegen, M., Lawlor, E. R. & Neubig, R. R. Jan 1 2017 In : Molecular Cancer Therapeutics. 16, 1, p. 193-204 12 p.

Research output: Contribution to journalArticle

Melanoma
Transcription Factors
Pharmacology
Neoplasm Metastasis
Lung

Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine

Waldschmidt, H. V., Homan, K. T., Cato, M. C., Cruz-Rodríguez, O., Cannavo, A., Wilson, M. W., Song, J., Cheung, J. Y., Koch, W. J., Tesmer, J. J. G. & Larsen, S. D. Apr 13 2017 In : Journal of Medicinal Chemistry. 60, 7, p. 3052-3069 18 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 2
Paroxetine
G-Protein-Coupled Receptor Kinases
Heterotrimeric GTP-Binding Proteins
Drug Design

Blockade of the renin–angiotensin system prevents acute and immunologically relevant colitis in murine models

Okawada, M., Wilson, M. W., Larsen, S. D., Lipka, E., Hillfinger, J. & Teitelbaum, D. H. Dec 1 2016 In : Pediatric Surgery International. 32, 12, p. 1103-1114 12 p.

Research output: Contribution to journalArticle

Colitis
Renin-Angiotensin System
Interleukin-10
Angiotensin Type 1 Receptor
Inbred C57BL Mouse