Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Mutation Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Cells Chemical Compounds
Autoimmune Lymphoproliferative Syndrome Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Leukemia Medicine & Life Sciences

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Grants 2009 2021

Research Output 2005 2017

  • 461 Citations
  • 10 h-Index
  • 11 Article
  • 1 Comment/debate
12 Citations

KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

Burgess, M. R. , Hwang, E. , Mroue, R. , Bielski, C. M. , Wandler, A. M. , Huang, B. J. , Firestone, A. J. , Young, A. , Lacap, J. A. , Crocker, L. , Asthana, S. , Davis, E. M. , Xu, J. , Akagi, K. , Le Beau, M. M. , Li, Q. , Haley, B. , Stokoe, D. , Sampath, D. , Taylor, B. S. & 2 others Evangelista, M. & Shannon, K. Feb 23 2017 In : Cell. 168, 5, p. 817-829.e15

Research output: Contribution to journalArticle

Allelic Imbalance
Mitogen-Activated Protein Kinase Kinases
Phosphotransferases
Acute Myeloid Leukemia
Clustered Regularly Interspaced Short Palindromic Repeats
2 Citations

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

Fenouille, N. , Bassil, C. F. , Ben-Sahra, I. , Benajiba, L. , Alexe, G. , Ramos, A. , Pikman, Y. , Conway, A. S. , Burgess, M. R. , Li, Q. , Luciano, F. , Auberger, P. , Galinsky, I. , Deangelo, D. J. , Stone, R. M. , Zhang, Y. , Perkins, A. S. , Shannon, K. , Hemann, M. T. , Puissant, A. & 1 others Stegmaier, K. Mar 1 2017 In : Nature medicine. 23, 3, p. 301-313 13 p.

Research output: Contribution to journalArticle

Creatine
Creatine Kinase
Metabolism
Acute Myeloid Leukemia
Small Interfering RNA
27 Citations

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia

Dail, M., Wong, J., Lawrence, J., O'Connor, D., Nakitandwe, J., Chen, S. C., Xu, J., Lee, L. B., Akagi, K., Li, Q., Aster, J. C., Pear, W. S., Downing, J. R., Sampath, D. & Shannon, K. Sep 25 2014 In : Nature. 513, 7519, p. 512-516 5 p.

Research output: Contribution to journalArticle

T-Cell Leukemia
1-Phosphatidylinositol 4-Kinase
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Notch1 Receptor
Clone Cells
27 Citations

Preclinical efficacy of MEK inhibition in NRAS-mutant AML

Burgess, M. R., Hwang, E., Firestone, A. J., Huang, T., Xu, J., Zuber, J., Bohin, N., Wen, T., Kogan, S. C., Haigis, K. M., Sampath, D., Lowe, S., Shannon, K. & Li, Q. Dec 18 2014 In : Blood. 124, 26, p. 3947-3955 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Hematopoietic Stem Cells
Acute Myeloid Leukemia
Phosphatidylinositol 3-Kinase
Small Interfering RNA
30 Citations

Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation

Xu, J., Haigis, K. M., Firestone, A. J., McNerney, M. E., Li, Q., Davis, E., Chen, S. C., Nakitandwe, J., Downing, J., Jacks, T., Le Beau, M. M. & Shannon, K. Sep 1 2013 In : Cancer Discovery. 3, 9, p. 993-1001 9 p.

Research output: Contribution to journalArticle

Oncogenes
Neoplasms
Mitogen-Activated Protein Kinase Kinases
Growth
Aptitude