Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Thyroglobulin Medicine & Life Sciences
Endoplasmic Reticulum Medicine & Life Sciences
Proinsulin Medicine & Life Sciences
Insulin Medicine & Life Sciences
Secretory Pathway Medicine & Life Sciences
Insulin-Secreting Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences
Secretory Vesicles Medicine & Life Sciences

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Grants 2003 2020

Research Output 1976 2018

Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP

Hussain, S. S., Harris, M. T., Kreutzberger, A. J. B., Inouye, C. M., Doyle, C. A., Castle, A. M., Arvan, P. & David Castle, J. May 15 2018 In : Molecular biology of the cell. 29, 10, p. 1238-1257 20 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Protein Binding
Cholesterol
Insulin
Insulin-Secreting Cells
1 Citations

Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity

Kim, G. H., Shi, G., Somlo, D. R. M., Haataja, L., Song, S., Long, Q., Nillni, E. A., Low, M. J., Arvan, P., Myers, M. G. & Qi, L. Mar 1 2018 In : Journal of Clinical Investigation. 128, 3, p. 1125-1140 16 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Obesity
Neurons
Cysteine
Hyperphagia

Increased mitochondrial respiration promotes survival from endoplasmic reticulum stress

Knupp, J., Arvan, P. & Chang, A. May 23 2018 (Accepted/In press) In : Cell Death and Differentiation. p. 1-15 15 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Respiration
Reactive Oxygen Species
Organelle Biogenesis
Yeasts

Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes

Arunagiri, A., Haataja, L., Cunningham, C. N., Shrestha, N., Tsai, B., Qi, L., Liu, M. & Arvan, P. Jan 1 2018 (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

Proinsulin
Medical problems
Endoplasmic Reticulum
Disulfides
Diabetes
1 Citations

Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins

Guo, H., Sun, J., Li, X., Xiong, Y., Wang, H., Shu, H., Zhu, R., Liu, Q., Huang, Y., Madley, R., Wang, Y., Cui, J., Arvan, P. & Liu, M. Jan 1 2018 In : Journal of Biological Chemistry. 293, 6, p. 1899-1907 9 p.

Research output: Contribution to journalReview article

Protein Sorting Signals
Medical problems
Type 2 Diabetes Mellitus
Secretory Rate
Defects