Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Thyroglobulin Medicine & Life Sciences
Endoplasmic Reticulum Medicine & Life Sciences
Proinsulin Medicine & Life Sciences
Insulin Medicine & Life Sciences
Secretory Pathway Medicine & Life Sciences
Insulin-Secreting Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences
Secretory Vesicles Medicine & Life Sciences

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Grants 2003 2020

Research Output 1976 2018

Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes

Arunagiri, A., Haataja, L., Cunningham, C. N., Shrestha, N., Tsai, B., Qi, L., Liu, M. & Arvan, P. Jan 1 2018 (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

Medical problems
Endoplasmic Reticulum
1 Citations

Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins

Guo, H., Sun, J., Li, X., Xiong, Y., Wang, H., Shu, H., Zhu, R., Liu, Q., Huang, Y., Madley, R., Wang, Y., Cui, J., Arvan, P. & Liu, M. Jan 1 2018 In : Journal of Biological Chemistry. 293, 6, p. 1899-1907 9 p.

Research output: Contribution to journalReview article

Protein Sorting Signals
Medical problems
Type 2 Diabetes Mellitus
Secretory Rate

Chaperone-driven degradation of a misfolded proinsulin mutant in parallel with restoration of wild-Type insulin secretion

Cunningham, C. N., He, K., Arunagiri, A., Paton, A. W., Paton, J. C., Arvan, P. & Tsai, B. Mar 1 2017 In : Diabetes. 66, 3, p. 741-753 13 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Molecular Weight
Endoplasmic Reticulum-Associated Degradation
1 Citations

De novo triiodothyronine formation from thyrocytes activated by Thyroid-stimulating hormone

Citterio, C. E., Veluswamy, B., Morgan, S. J., Galton, V. A., Banga, J. P., Atkins, S., Morishita, Y., Neumann, S., Latif, R., Gershengorn, M. C., Smith, T. J. & Arvan, P. 2017 In : Journal of Biological Chemistry. 292, 37, p. 15434-15444 11 p.

Research output: Contribution to journalArticle

Thyrotropin Receptors
2 Citations

ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis

Shi, G., Somlo, D., Kim, G. H., Prescianotto-Baschong, C., Sun, S., Beuret, N., Long, Q., Rutishauser, J., Arvan, P., Spiess, M. & Qi, L. Oct 2 2017 In : Journal of Clinical Investigation. 127, 10, p. 3897-3912 16 p.

Research output: Contribution to journalArticle

Peptide Hormones
Protein Disulfide-Isomerases