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  • 6 Similar Profiles
Genetic Therapy Medicine & Life Sciences
Brain Medicine & Life Sciences
Adenoviridae Medicine & Life Sciences
Genes Medicine & Life Sciences
Glioma Medicine & Life Sciences
Transgenes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences

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Grants 2011 2021

Research Output 1979 2017

Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

Kamran, N., Kadiyala, P., Saxena, M., Candolfi, M., Li, Y., Moreno-Ayala, M. A., Raja, N., Shah, D., Lowenstein, P. R. & Castro, M. G. Jan 4 2017 In : Molecular Therapy. 25, 1, p. 232-248 17 p.

Research output: Contribution to journalArticle

Myeloid Cells
Immunosuppressive Agents
Glioma
Genetic Therapy
Neoplasms

Matrix metalloproteinase activity in infections by an encephalitic virus, mouse adenovirus type 1

Ashley, S. L., Pretto, C. D., Stier, M. T., Kadiyala, P., Castro-Jorge, L., Hsu, T. H., Doherty, R., Carnahan, K. E., Castro, M. G., Lowenstein, P. R. & Spindler, K. R. 2017 In : Journal of Virology. 91, 6, e01412-16

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Adenoviridae
Viruses
Infection
Brain
2 Citations

Survival and proliferation of neural progenitor-derived glioblastomas under hypoxic stress is controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism

Calinescu, A. A., Yadav, V. N., Carballo, E., Kadiyala, P., Tran, D., Zamler, D. B., Doherty, R., Srikanth, M., Lowenstein, P. R. & Castro, M. G. Mar 1 2017 In : Clinical Cancer Research. 23, 5, p. 1250-1262 13 p.

Research output: Contribution to journalArticle

Glioblastoma
Stem Cells
Glioma
Cell Cycle
Neoplasms
10 Citations

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

Koschmann, C. , Calinescu, A. A. , Nunez, F. J. , Mackay, A. , Fazal-Salom, J. , Thomas, D. , Mendez, F. , Kamran, N. , Dzaman, M. , Mulpuri, L. , Krasinkiewicz, J. , Doherty, R. , Lemons, R. , Brosnan-Cashman, J. A. , Li, Y. , Roh, S. , Zhao, L. , Appelman, H. , Ferguson, D. , Gorbunova, V. & 4 others Meeker, A., Jones, C., Lowenstein, P. R. & Castro, M. G. Mar 2 2016 In : Science Translational Medicine. 8, 328, 328ra28

Research output: Contribution to journalArticle

DNA End-Joining Repair
Glioblastoma
Glioma
Mutation
DNA
1 Citations

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

Koschmann, C., Zamler, D., MacKay, A., Robinson, D., Wu, Y. M., Doherty, R., Marini, B., Tran, D., Garton, H., Muraszko, K., Robertson, P., Leonard, M., Zhao, L., Bixby, D., Peterson, L., Camelo-Piragua, S., Jones, C., Mody, R., Lowenstein, P. R. & Castro, M. G. 2016 In : Oncotarget. 7, 40, p. 65696-65706 11 p.

Research output: Contribution to journalArticle

Glioma
Pediatrics
Mutation
Datasets
Primary Cell Culture