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  • 5 Similar Profiles
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Medicine & Life Sciences
Interferon-alpha Medicine & Life Sciences
Philadelphia Chromosome Medicine & Life Sciences
Cytogenetics Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Leukemia, Myeloid, Chronic Phase Medicine & Life Sciences
Mesylates Medicine & Life Sciences
Bone Marrow Medicine & Life Sciences

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Grants 2006 2026

Research Output 1979 2017

Induction of p53 suppresses chronic myeloid leukemia

Peterson, L. F., Lo, M. C., Liu, Y., Giannola, D., Mitrikeska, E., Donato, N. J., Johnson, C. N., Wang, S., Mercer, J. & Talpaz, M. Jan 13 2017 In : Leukemia and Lymphoma. p. 1-14 14 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Philadelphia Chromosome
Myeloid Cells
Cell Cycle
2 Citations

Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial

Verstovsek, S. , Mesa, R. A. , Gotlib, J. , Gupta, V. , DiPersio, J. F. , Catalano, J. V. , Deininger, M. W. N. , Miller, C. B. , Silver, R. T. , Talpaz, M. , Winton, E. F. , Harvey, J. H. , Arcasoy, M. O. , Hexner, E. O. , Lyons, R. M. , Paquette, R. , Raza, A. , Jones, M. , Kornacki, D. , Sun, K. & 1 others Kantarjian, H. Feb 22 2017 In : Journal of Hematology and Oncology. 10, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Placebos
Spleen
Safety
Splenomegaly

Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia

Cortes, J., Talpaz, M., Smith, H. P., Snyder, D. S., Khoury, J., Bhalla, K. N., Pinilla-Ibarz, J., Larson, R., Mitchell, D., Wise, S. C., Rutkoski, T. J., Smith, B. D., Flynn, D. L., Kantarjian, H. M., Rosen, O. & Van Etten, R. A. Feb 28 2017 In : Haematologica. 102, 3, p. 519-528 10 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Acute Myeloid Leukemia
Tablets
Mutation
Maximum Tolerated Dose
2 Citations

Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis

Mascarenhas, J. O., Talpaz, M., Gupta, V., Foltz, L. M., Savona, M. R., Paquette, R., Turner, A. R., Coughlin, P., Winton, E., Burn, T. C., O'neill, P., Clark, J., Hunter, D., Assad, A., Hoffman, R. & Verstovsek, S. 2017 In : Haematologica. 102, 2, p. 327-335 9 p.

Research output: Contribution to journalArticle

Janus Kinase 1
Primary Myelofibrosis
Thrombocytopenia
Spleen
Erythrocyte Transfusion

Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma

Potu, H., Peterson, L. F., Kandarpa, M., Pal, A., Sun, H., Durham, A., Harms, P. W., Hollenhorst, P. C., Eskiocak, U., Talpaz, M. & Donato, N. J. Feb 15 2017 In : Nature Communications. 8, 14449

Research output: Contribution to journalArticle

Ubiquitination
Melanoma
destruction
Skin
Neoplasms