Matthew A Young

  • 3571 Citations
  • 25 Scopus h-Index
19942017

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Molecular Dynamics Simulation Medicine & Life Sciences
DNA Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
B-Form DNA Medicine & Life Sciences
Molecular dynamics Engineering & Materials Science
Protein-Tyrosine Kinases Medicine & Life Sciences
Computer simulation Engineering & Materials Science

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Grants 2005 2017

Research Output 1994 2015

  • 3571 Citations
  • 25 Scopus h-Index
  • 36 Article
  • 1 Chapter
  • 1 Review article
3 Citations

Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling

Young, M. & 25 others Chou, D. H. C., Vetere, A., Choudhary, A., Scully, S. S., Schenone, M., Tang, A., Gomez, R., Burns, S. M., Lundh, M., Vital, T., Comer, E., Faloon, P. W., Dančík, V., Ciarlo, C., Paulk, J., Dai, M., Reddy, C., Sun, H., Donato, N., Jaffe, J., Clemons, P. A., Palmer, M., Carr, S. A., Schreiber, S. L. & Wagner, B. K. Jun 24 2015 In : Journal of the American Chemical Society. 137, 24, p. 7929-7934 6 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Ubiquitin
Peptide Hydrolases
Phosphotransferases
Molecules
4 Citations

Targeted inhibition of the Shroom3-Rho kinase protein-protein interaction circumvents Nogo66 to promote axon outgrowth

Dickson, H. M., Wilbur, A., Reinke, A. A., Young, M. A. & Vojtek, A. B. Jun 16 2015 In : BMC Neuroscience. 16, 1, 34

Research output: Contribution to journalArticle

rho-Associated Kinases
Axons
Proteins
Neurites
Myosins
13 Citations

Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies

Peterson, L. F., Sun, H., Liu, Y., Potu, H., Kandarpa, M., Ermann, M., Courtney, S. M., Young, M., Showalter, H. D., Sun, D., Jakubowiak, A., Malek, S. N., Talpaz, M. & Donato, N. J. Jun 4 2015 In : Blood. 125, 23, p. 3588-3597 10 p.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
B-Lymphocytes
Apoptosis
Neoplasms
Proteins
7 Citations

Degrasyn-like symmetrical compounds: Possible therapeutic agents for multiple myeloma (MM-I)

Peng, Z., Maxwell, D. S., Sun, D., Bhanu Prasad, B. A., Schuber, P. T., Pal, A., Ying, Y., Han, D., Gao, L., Wang, S., Levitzki, A., Kapuria, V., Talpaz, M., Young, M., Showalter, H. D., Donato, N. J. & Bornmann, W. G. Feb 15 2014 In : Bioorganic and Medicinal Chemistry. 22, 4, p. 1450-1458 9 p.

Research output: Contribution to journalArticle

Neoplasms
Mantle-Cell Lymphoma
Multiple Myeloma
B-Lymphocytes
Cell Line
40 Citations

Emerging potential of therapeutic targeting of ubiquitin-specific proteases in the treatment of cancer

Pal, A., Young, M. A. & Donato, N. J. Aug 29 2014 In : Cancer Research. 74, 18, p. 4955-4966 12 p.

Research output: Contribution to journalReview article

Ubiquitin-Specific Proteases
Neoplasms
Proteasome Endopeptidase Complex
Ubiquitin
Proteins