Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 10 Similar Profiles
Neoplasms Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Butyrates Medicine & Life Sciences
Inhibitor of Apoptosis Proteins Medicine & Life Sciences
Genes Medicine & Life Sciences
Castration Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2009 2022

Research Output 2000 2017

  • 1358 Citations
  • 23 Scopus h-Index
  • 38 Article
  • 4 Review article
  • 2 Comment/debate

Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor

Zhao, Y., Bai, L., Liu, L., McEachern, D., Stuckey, J. A., Meagher, J. L., Yang, C. Y., Ran, X., Zhou, B., Hu, Y., Li, X., Wen, B., Zhao, T., Li, S., Sun, D. & Wang, S. May 11 2017 In : Journal of Medicinal Chemistry. 60, 9, p. 3887-3901 15 p.

Research output: Contribution to journalArticle

Proteins
Leukemia
Triple Negative Breast Neoplasms
Heterografts
Pharmacokinetics
2 Citations

Targeted degradation of BET proteins in triple-negative breast cancer

Bai, L. , Zhou, B. , Yang, C. Y. , Ji, J. , McEachern, D. , Przybranowski, S. , Jiang, H. , Hu, J. , Xu, F. , Zhao, Y. , Liu, L. , Fernandez-Salas, E. , Xu, J. , Dou, Y. , Wen, B. , Sun, D. , Meagher, J. , Stuckey, J. , Hayes, D. F. , Li, S. & 2 others Ellis, M. J. & Wang, S. May 1 2017 In : Cancer Research. 77, 9, p. 2476-2487 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Proteolysis
Apoptosis
Genes
Down-Regulation
1 Citations

Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors

Yang, C. Y., Phillips, J. G., Stuckey, J. A., Bai, L., Sun, H., Delproposto, J., Brown, W. C. & Chinnaswamy, K. Dec 8 2016 In : ACS Medicinal Chemistry Letters. 7, 12, p. 1092-1096 5 p.

Research output: Contribution to journalArticle

Complement Factor D
Hydrogen
Amides
Alternative Complement Pathway
Cape Verde
24 Citations

Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors

Ran, X., Zhao, Y., Liu, L., Bai, L., Yang, C. Y., Zhou, B., Meagher, J. L., Chinnaswamy, K., Stuckey, J. A. & Wang, S. Jun 25 2015 In : Journal of Medicinal Chemistry. 58, 12, p. 4927-4939 13 p.

Research output: Contribution to journalArticle

Carbolines
Proteins
Leukemia
Neoplasms
Cell Line
23 Citations

BM-1197: A novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo

Bai, L., Chen, J., McEachern, D., Liu, L., Zhou, H., Aguilar, A. & Wang, S. Jun 5 2014 In : PLoS One. 9, 6, e99404

Research output: Contribution to journalArticle

remission
lung neoplasms
apoptosis
neoplasms
mice