Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Floxuridine Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Thioguanine Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Deoxyuridine Medicine & Life Sciences
DNA Medicine & Life Sciences
HT29 Cells Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences

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Grants 1987 2019

Research Output 1979 2018

  • 2640 Citations
  • 31 h-Index
  • 76 Article
  • 2 Review article
  • 1 Letter

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors

Parsels, L. A., Karnak, D., Parsels, J. D., Zhang, Q., Velez-Padilla, J., Reichert, Z. R., Wahl, D. R., Maybaum, J., O'Connor, M. J., Lawrence, T. S. & Morgan, M. A. Feb 1 2018 In : Molecular Cancer Research. 16, 2, p. 222-232 11 p.

Research output: Contribution to journalArticle

DNA Replication
Non-Small Cell Lung Carcinoma
Nucleotides
DNA Damage
Nucleosides
5 Citations

Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry

Parsels, L. A., Tanska, D. M., Parsels, J. D., Zabludoff, S. D., Cuneo, K. C., Lawrence, T. S., Maybaum, J. & Morgan, M. A. Mar 3 2016 In : Cell Cycle. 15, 5, p. 730-739 10 p.

Research output: Contribution to journalArticle

gemcitabine
Cell Cycle Checkpoints
Pancreatic Neoplasms
Cyclin B1
Cell Line
12 Citations

Wee1 kinase inhibitor AZD1775 radiosensitizes hepatocellular carcinoma regardless of TP53 mutational status through induction of replication stress

Cuneo, K. C., Morgan, M. A., Davis, M. A., Parcels, L. A., Parcels, J., Karnak, D., Ryan, C., Liu, N., Maybaum, J. & Lawrence, T. S. Jun 1 2016 In : International Journal of Radiation Oncology Biology Physics. 95, 2, p. 782-790 9 p.

Research output: Contribution to journalArticle

inhibitors
Hepatocellular Carcinoma
induction
Phosphotransferases
cancer
14 Citations

Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair

Kausar, T., Schreiber, J. S., Karnak, D., Parsels, L. A., Parsels, J. D., Davis, M. A., Zhao, L., Maybaum, J., Lawrence, T. S. & Morgan, M. A. Jan 1 2015 In : Neoplasia. 17, 10, p. 757-766 10 p.

Research output: Contribution to journalArticle

gemcitabine
Recombinational DNA Repair
Pancreatic Neoplasms
Phosphotransferases
Radiation
35 Citations

Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer

Karnak, D., Engelke, C. G., Parsels, L. A., Kausar, T., Wei, D., Robertson, J. R., Marsh, K. B., Davis, M. A., Zhao, L., Maybaum, J., Lawrence, T. S. & Morgan, M. A. Oct 1 2014 In : Clinical Cancer Research. 20, 19, p. 5085-5096 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Recombinational DNA Repair
Radiation
DNA Damage
Survival