Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Proteins Medicine & Life Sciences
Leucyl Aminopeptidase Chemical Compounds
Leukemia Medicine & Life Sciences
Enzymes Chemical Compounds
Therapeutics Medicine & Life Sciences
Dipeptides Chemical Compounds
Neoplasms Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences

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Grants 2009 2022

Research Output 1997 2017

  • 1752 Citations
  • 24 Scopus h-Index
  • 54 Article
  • 4 Review article
  • 1 Editorial
  • 1 Short survey

Stabilizing the mixed lineage leukemia protein

Grembecka, J. & Cierpicki, T. Apr 27 2017 In : New England Journal of Medicine. 376, 17, p. 1688-1689 2 p.

Research output: Research - peer-reviewShort survey

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Svoboda, L. K., Bailey, N., Van Noord, R. A., Krook, M. A., Harris, A., Cramer, C., Jasman, B., Patel, R. M., Thomas, D., Borkin, D., Cierpicki, T., Grembecka, J. & Lawlor, E. R. 2017 In : Oncotarget. 8, 1, p. 458-471 14 p.

Research output: Research - peer-reviewArticle

Ewing's Sarcoma
Proteins
Transcriptional Activation
Neoplasms
Leukemia
1 Citations

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

Gray, F., Cho, H. J., Shukla, S., He, S., Harris, A., Boytsov, B., Jaremko, A., Jaremko, M., Demeler, B., Lawlor, E. R., Grembecka, J. & Cierpicki, T. Nov 9 2016 In : Nature Communications. 7, 13343

Research output: Research - peer-reviewArticle

Polycomb Repressive Complex 1
Oligomerization
Thermodynamic properties
Proteins
proteins
1 Citations

H3K36 methyltransferases as cancer drug targets: Rationale and perspectives for inhibitor development

Rogawski, D. S., Grembecka, J. & Cierpicki, T. Sep 1 2016 In : Future Medicinal Chemistry. 8, 13, p. 1589-1607 19 p.

Research output: Research - peer-reviewReview article

Methyltransferases
Pharmaceutical Preparations
Genes
Neoplasms
Genetic Translocation
3 Citations

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)

Borkin, D., Pollock, J., Kempinska, K., Purohit, T., Li, X., Wen, B., Zhao, T., Miao, H., Shukla, S., He, M., Sun, D., Cierpicki, T. & Grembecka, J. Feb 11 2016 In : Journal of Medicinal Chemistry. 59, 3, p. 892-913 22 p.

Research output: Research - peer-reviewArticle

Leukemia
Proteins
Lead
Myeloid-Lymphoid Leukemia Protein
Biphenotypic Acute Leukemia