Personal profile

Research interests

We are interested in the development of therapeutics and diagnostics at the interface of immunology and engineering. Specifically, we are working on drug delivery systems for enhancing delivery of antigen and adjuvant to lymphoid organs and manipulating immune functions in the context of cancer, infectious diseases, and autoimmunity. Our focus is on translational research using nanotechnology, biomaterials, drug delivery, cell and tissue engineering to detect and improve immune responses in vivo. Current projects include design of biomaterials to recruit and expand cytotoxic CD8 T cells to eradicate metastatic tumors and prevent HIV infection.

Keywords

  • vaccine
  • nanotechnology
  • biomaterials
  • immunology

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Vaccines Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Hydrogels Engineering & Materials Science
Antigens Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Vaccination Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Lipids Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2017

  • 2595 Citations
  • 24 Scopus h-Index
  • 29 Article
  • 2 Review article
  • 1 Chapter
  • 1 Conference contribution
Cross-Priming
Antigen Presentation
Liposomes
Dendritic Cells
Antigens
Bioterrorism
Vaccination
Vaccines
Pathogens
Disease Outbreaks
11 Citations

High-Density Lipoproteins: Nature's Multifunctional Nanoparticles

Kuai, R., Li, D., Chen, Y. E., Moon, J. J. & Schwendeman, A. Mar 22 2016 In : ACS Nano. 10, 3, p. 3015-3041 27 p.

Research output: Contribution to journalArticle

Lipoproteins
Cholesterol
Nanoparticles
Proteins
Drug delivery
3 Citations

Synthetic high-density lipoprotein nanoparticles: A novel therapeutic strategy for adrenocortical carcinomas

Subramanian, C., Kuai, R., Zhu, Q., White, P., Moon, J. J., Schwendeman, A. & Cohen, M. S. Jan 1 2016 In : Surgery. 159, 1, p. 284-294 11 p.

Research output: Contribution to journalArticle

Adrenocortical Carcinoma
HDL Lipoproteins
Nanoparticles
Cholesterol
Hydrocortisone
16 Citations

Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens

Fan, Y., Sahdev, P., Ochyl, L. J., J. Akerberg, J. & Moon, J. J. Jun 28 2015 In : Journal of Controlled Release. 208, p. 121-129 9 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Liposomes
Nanoparticles
Vaccination
Antigens