Personal profile

Research interests

We are interested in the development of therapeutics and diagnostics at the interface of immunology and engineering. Specifically, we are working on drug delivery systems for enhancing delivery of antigen and adjuvant to lymphoid organs and manipulating immune functions in the context of cancer, infectious diseases, and autoimmunity. Our focus is on translational research using nanotechnology, biomaterials, drug delivery, cell and tissue engineering to detect and improve immune responses in vivo. Current projects include design of biomaterials to recruit and expand cytotoxic CD8 T cells to eradicate metastatic tumors and prevent HIV infection.

Keywords

  • vaccine
  • nanotechnology
  • biomaterials
  • immunology

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 2003 2017

  • 2937 Citations
  • 25 Scopus h-Index
  • 36 Article
  • 3 Review article
  • 1 Chapter
  • 1 Conference contribution

Adjuvant-Loaded Spiky Gold Nanoparticles for Activation of Innate Immune Cells

Nam, J., Son, S. & Moon, J. J. Oct 1 2017 In : Cellular and Molecular Bioengineering. 10, 5, p. 341-355 15 p.

Research output: Research - peer-reviewArticle

Gold
Chemical activation
Nanoparticles
Gold Nanoparticles
Activation
Cross-Priming
Antigen Presentation
Liposomes
Dendritic Cells
Antigens
1 Citations

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting

Tang, J., Kuai, R., Yuan, W., Drake, L., Moon, J. J. & Schwendeman, A. Aug 1 2017 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 6, p. 1869-1878 10 p.

Research output: Research - peer-reviewArticle

HDL Lipoproteins
Liposomes
Lipoproteins
Tumors
Nanoparticles
Biological Warfare Agents
Vaccination
Vaccines
Pathogens
Bioterrorism

Self-encapsulating Poly(lactic-co-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery

Bailey, B. A., Desai, K. G. H., Ochyl, L. J., Ciotti, S. M., Moon, J. J. & Schwendeman, S. P. Sep 5 2017 In : Molecular Pharmaceutics. 14, 9, p. 3228-3237 10 p.

Research output: Research - peer-reviewArticle

Microspheres
Vaccines
polylactic acid-polyglycolic acid copolymer
Ovalbumin
Cholera Toxin