Personal profile

Research interests

We are interested in the development of therapeutics and diagnostics at the interface of immunology and engineering. Specifically, we are working on drug delivery systems for enhancing delivery of antigen and adjuvant to lymphoid organs and manipulating immune functions in the context of cancer, infectious diseases, and autoimmunity. Our focus is on translational research using nanotechnology, biomaterials, drug delivery, cell and tissue engineering to detect and improve immune responses in vivo. Current projects include design of biomaterials to recruit and expand cytotoxic CD8 T cells to eradicate metastatic tumors and prevent HIV infection.


  • vaccine
  • nanotechnology
  • biomaterials
  • immunology

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Nanoparticles Medicine & Life Sciences
Vaccines Engineering & Materials Science
Hydrogels Medicine & Life Sciences
Antigens Engineering & Materials Science
Lipoproteins Engineering & Materials Science
HDL Lipoproteins Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Vaccination Medicine & Life Sciences

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Research Output 2003 2018

  • 3101 Citations
  • 27 h-Index
  • 39 Article
  • 3 Review article
  • 1 Chapter
  • 1 Conference contribution

High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia

Park, H. J., Kuai, R., Jeon, E. J., Seo, Y., Jung, Y., Moon, J. J., Schwendeman, A. & Cho, S. W. Apr 1 2018 In : Biomaterials. 161, p. 69-80 12 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Substance P

Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression

Guo, Y., Yuan, W., Yu, B., Kuai, R., Hu, W., Morin, E. E., Garcia-Barrio, M. T., Zhang, J., Moon, J. J., Schwendeman, A. & Eugene Chen, Y. Jan 1 2018 (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

HDL Lipoproteins
Computer simulation
1 Citations

Adjuvant-Loaded Spiky Gold Nanoparticles for Activation of Innate Immune Cells

Nam, J., Son, S. & Moon, J. J. Oct 1 2017 In : Cellular and Molecular Bioengineering. 10, 5, p. 341-355 15 p.

Research output: Contribution to journalArticle

Gold Nanoparticles
Chemical activation
4 Citations
Antigen Presentation
Dendritic Cells
4 Citations

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting

Tang, J., Kuai, R., Yuan, W., Drake, L., Moon, J. J. & Schwendeman, A. Aug 1 2017 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 6, p. 1869-1878 10 p.

Research output: Contribution to journalArticle

HDL Lipoproteins