Personal profile

Research interests

We are interested in the development of therapeutics and diagnostics at the interface of immunology and engineering. Specifically, we are working on drug delivery systems for enhancing delivery of antigen and adjuvant to lymphoid organs and manipulating immune functions in the context of cancer, infectious diseases, and autoimmunity. Our focus is on translational research using nanotechnology, biomaterials, drug delivery, cell and tissue engineering to detect and improve immune responses in vivo. Current projects include design of biomaterials to recruit and expand cytotoxic CD8 T cells to eradicate metastatic tumors and prevent HIV infection.

Keywords

  • vaccine
  • nanotechnology
  • biomaterials
  • immunology

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Nanoparticles Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Antigens Medicine & Life Sciences
Hydrogels Medicine & Life Sciences
Myosins Chemical Compounds
Vaccination Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Polyethylene glycols Engineering & Materials Science

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2017

  • 2767 Citations
  • 24 Scopus h-Index
  • 33 Article
  • 3 Review article
  • 1 Chapter
  • 1 Conference contribution
Cross-Priming
Antigen Presentation
Liposomes
Dendritic Cells
Antigens

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting

Tang, J., Kuai, R., Yuan, W., Drake, L., Moon, J. J. & Schwendeman, A. Aug 1 2017 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 6, p. 1869-1878 10 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Liposomes
Nanoparticles
Lipoproteins
Peptides
Bioterrorism
Vaccination
Vaccines
Inborn Errors Amino Acid Metabolism
Pathogens

Toward a Single-Dose Vaccination Strategy with Self-Encapsulating PLGA Microspheres

Bailey, B. A., Ochyl, L. J., Schwendeman, S. P. & Moon, J. J. 2017 In : Advanced Healthcare Materials.

Research output: Contribution to journalArticle

Microspheres
Milk
Vaccination
Acids
Antigens

Vaccine nanoparticles for protection against HIV infection

Aikins, M. E., Bazzill, J. & Moon, J. J. Mar 1 2017 In : Nanomedicine. 12, 6, p. 673-682 10 p.

Research output: Contribution to journalArticle

Nanoparticles
HIV Infections
HIV-1
Vaccines
therapy