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  • 7 Similar Profiles
Genes Medicine & Life Sciences
Cyclic AMP Receptor Protein Chemical Compounds
beta-Globins Medicine & Life Sciences
Chickens Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Proteins Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences

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Grants 2002 2020

Research Output 1971 2017

Derepression of the DNA methylation machinery of the Gata1 gene triggers the differentiation cue for erythropoiesis

Yu, L., Takai, J., Otsuki, A., Katsuoka, F., Suzuki, M., Katayama, S., Nezu, M., Engel, J. D., Moriguchi, T. & Yamamoto, M. Apr 1 2017 In : Molecular and Cellular Biology. 37, 8, e00592-16

Research output: Contribution to journalArticle

Erythropoiesis
DNA Methylation
Methylation
Cues
Genes

GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis

Katayama, S., Suzuki, M., Yamaoka, A., Keleku-Lukwete, N., Katsuoka, F., Otsuki, A., Kure, S., Engel, J. D. & Yamamoto, M. Aug 17 2017 In : Blood. 130, 7, p. 908-919 12 p.

Research output: Contribution to journalArticle

Methacholine Compounds
Cyclic AMP Receptor Protein
Haploinsufficiency
Leukemia
Saimiriine herpesvirus 2

GATA3 abundance is a critical determinant of T cell receptor β allelic exclusion

Ku, C. J., Sekiguchi, J. A. M., Panwar, B., Guan, Y., Takahashi, S., Yoh, K., Maillard, I., Hosoya, T. & Engel, J. D. Jun 1 2017 In : Molecular and Cellular Biology. 37, 12, e00052-17

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Alleles
Genetic Recombination
T-Cell Receptor beta Genes
Gene Rearrangement

Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation

Zhang, Y., Zhang, J., An, W., Wan, Y., Ma, S., Yin, J., Li, X., Gao, J., Yuan, W., Guo, Y., Engel, J. D., Shi, L., Cheng, T. & Zhu, X. 2017 In : Nucleic Acids Research. 45, 2, p. 657-671 15 p.

Research output: Contribution to journalArticle

Introns
Sideroblastic Anemia
Mutation
Clustered Regularly Interspaced Short Palindromic Repeats
5-Aminolevulinate Synthetase

Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease

Jagadeeswaran, R., Vazquez, B. A., Thiruppathi, M., Ganesh, B. B., Ibanez, V., Cui, S., Engel, J. D., Diamond, A. M., Molokie, R. E., DeSimone, J., Lavelle, D. & Rivers, A. Jan 3 2017 In : Experimental Hematology.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Sirolimus
Reactive Oxygen Species
Erythrocytes
Pharmacology