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  • 15 Similar Profiles
Neoplasms Medicine & Life Sciences
Matrix Metalloproteinase 7 Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Matrix Metalloproteinases Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Tumors Chemical Compounds
Metaplasia Medicine & Life Sciences

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Grants 2015 2021

Research Output 1994 2017

Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice

Zhang, Y., Yan, W., Mathew, E., Kane, K. T., Brannon, A., Adoumie, M., Vinta, A., Crawford, H. C. & di Magliano, M. P. Oct 5 2017 In : eLife. 6, e27388

Research output: Research - peer-reviewArticle

Acinar Cells
Myeloid Cells
Epithelial Cells
Cell Plasticity
Crosstalk
2 Citations

Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis

Halbrook, C. J., Wen, H. J., Ruggeri, J. M., Takeuchi, K. K., Zhang, Y., Pasca di Magliano, M. & Crawford, H. C. Jan 1 2017 In : CMGH. 3, 1, p. 99-118 20 p.

Research output: Research - peer-reviewArticle

Mitogen-Activated Protein Kinase Kinases
Metaplasia
Pancreatitis
Regeneration
Mitogen-Activated Protein Kinases

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A. S. , Joly, M. M. , Allen-Petersen, B. L. , Worth, P. J. , Lanciault, C. , Sauer, D. , Link, J. , Pelz, C. , Heiser, L. M. , Morton, J. P. , Muthalagu, N. , Hoffman, M. T. , Manning, S. L. , Pratt, E. D. , Kendsersky, N. D. , Egbukichi, N. , Amery, T. S. , Thoma, M. C. , Jenny, Z. P. , Rhim, A. D. & 5 others Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. C. & Sears, R. C. Dec 1 2017 In : Nature Communications. 8, 1, 1728

Research output: Research - peer-reviewArticle

Synaptophysin
Adenocarcinoma
Neoplasms
Plasticity
Tumors
14 Citations

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer

Saloman, J. L., Albers, K. M., Li, D., Hartman, D. J., Crawford, H. C., Muha, E. A., Rhim, A. D. & Davis, B. M. Mar 15 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 11, p. 3078-3083 6 p.

Research output: Research - peer-reviewArticle

Genetic Models
Sensory Receptor Cells
Adenocarcinoma
Neoplasms
Pancreas
7 Citations

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice with Activated KRAS

Qiu, W., Tang, S. M., Lee, S., Turk, A. T., Sireci, A. N., Qiu, A., Rose, C., Xie, C., Kitajewski, J., Wen, H. J., Crawford, H. C., Sims, P. A., Hruban, R. H., Remotti, H. E. & Su, G. H. Jan 1 2016 In : Gastroenterology. 150, 1, p. 218-228.e12

Research output: Research - peer-reviewArticle

Activin Receptors
Neoplasms
Carcinogenesis
Growth
Activins