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  • 14 Similar Profiles
Neoplasms Medicine & Life Sciences
Matrix Metalloproteinase 7 Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Matrix Metalloproteinases Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Tumors Chemical Compounds
Carcinogenesis Medicine & Life Sciences
Metaplasia Medicine & Life Sciences

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Grants 2015 2021

Research Output 1994 2017

1 Citations
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinases
10 Citations

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer

Saloman, J. L., Albers, K. M., Li, D., Hartman, D. J., Crawford, H. C., Muha, E. A., Rhim, A. D. & Davis, B. M. Mar 15 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 11, p. 3078-3083 6 p.

Research output: Research - peer-reviewArticle

Genetic Models
Sensory Receptor Cells
4 Citations

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice with Activated KRAS

Qiu, W., Tang, S. M., Lee, S., Turk, A. T., Sireci, A. N., Qiu, A., Rose, C., Xie, C., Kitajewski, J., Wen, H. J., Crawford, H. C., Sims, P. A., Hruban, R. H., Remotti, H. E. & Su, G. H. Jan 1 2016 In : Gastroenterology. 150, 1, p. 218-228.e12

Research output: Research - peer-reviewArticle

Activin Receptors
18 Citations

Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions

Liou, G. Y., Döppler, H., DelGiorno, K. E., Zhang, L., Leitges, M., Crawford, H. C., Murphy, M. P. & Storz, P. Mar 15 2016 In : Cell Reports. 14, 10, p. 2325-2336 12 p.

Research output: Research - peer-reviewArticle

Acinar Cells
Pancreatic Neoplasms
Reactive Oxygen Species
Intercellular Signaling Peptides and Proteins
Oxidative Stress
31 Citations

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer

Chio, I. I. C. , Jafarnejad, S. M. , Ponz-Sarvise, M. , Park, Y. , Rivera, K. , Palm, W. , Wilson, J. , Sangar, V. , Hao, Y. , Öhlund, D. , Wright, K. , Filippini, D. , Lee, E. J. , Da Silva, B. , Schoepfer, C. , Wilkinson, J. E. , Buscaglia, J. M. , DeNicola, G. M. , Tiriac, H. , Hammell, M. & 6 others Crawford, H. C., Schmidt, E. E., Thompson, C. B., Pappin, D. J., Sonenberg, N. & Tuveson, D. A. Aug 11 2016 In : Cell. 166, 4, p. 963-976 14 p.

Research output: Research - peer-reviewArticle

Epidermal Growth Factor Receptor
Messenger RNA
Protein Biosynthesis
Pancreatic Neoplasms