Hollis D Showalter

  • 4453 Citations
  • 40 Scopus h-Index
1972 …2020

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Protein-Tyrosine Kinases Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Amines Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Diamines Medicine & Life Sciences

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Grants 2008 2020

Research Output 1972 2016

  • 4453 Citations
  • 40 Scopus h-Index
  • 117 Article
  • 6 Comment/debate
  • 6 Review article
  • 3 Letter
1 Citations

Anti-infective activity of 2-cyano-3-acrylamide inhibitors with improved drug-like properties against two intracellular pathogens

Passalacqua, K. D., Charbonneau, M. E., Donato, N. J., Showalter, H. D., Sun, D., Wen, B., He, M., Sun, H., O'Riordan, M. X. D. & Wobus, C. E. Jul 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 7, p. 4183-4196 14 p.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
Acrylamide
Macrophages
Norovirus
Ubiquitin

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C

Carpenter, C., Sorenson, R. J., Jin, Y., Klossowski, S., Cierpicki, T., Gnegy, M. & Showalter, H. D. 2016 In : Bioorganic and Medicinal Chemistry. 24, 21, p. 5495-5504 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Protein Kinase C
Amphetamine-Related Disorders
Inhibition (Psychology)
Acrylonitrile
Adenosine
Amines
Amination
Nucleosides
4 Citations

Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes

Xu, H., Majmudar, J. D., Davda, D., Ghanakota, P., Kim, K. H., Carlson, H. A., Showalter, H. D., Martin, B. R. & Amidon, G. L. Sep 8 2015 In : Molecular Pharmaceutics. 12, 9, p. 3399-3407 9 p.

Research output: Contribution to journalArticle

Prodrugs
Esters
Enzymes
Oseltamivir
Carboxylesterase
13 Citations

Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies

Peterson, L. F., Sun, H., Liu, Y., Potu, H., Kandarpa, M., Ermann, M., Courtney, S. M., Young, M., Showalter, H. D., Sun, D., Jakubowiak, A., Malek, S. N., Talpaz, M. & Donato, N. J. Jun 4 2015 In : Blood. 125, 23, p. 3588-3597 10 p.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
B-Lymphocytes
Apoptosis
Neoplasms
Proteins