Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Pharmaceutical Preparations Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
HSP90 Heat-Shock Proteins Medicine & Life Sciences

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Grants 1997 2022

Research Output 1989 2018

4 Citations

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Zhou, B., Hu, J., Xu, F., Chen, Z., Bai, L., Fernandez-Salas, E., Lin, M., Liu, L., Yang, C. Y., Zhao, Y., McEachern, D., Przybranowski, S., Wen, B., Sun, D. & Wang, S. Jan 25 2018 In : Journal of medicinal chemistry. 61, 2, p. 462-481 20 p.

Research output: Contribution to journalArticle


Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability

Zwicker, J. D., Diaz, N. A., Guerra, A. J., Kirchhoff, P. D., Wen, B., Sun, D., Carruthers, V. B. & Larsen, S. D. Jun 1 2018 In : Bioorganic and Medicinal Chemistry Letters. 28, 10, p. 1972-1980 9 p.

Research output: Contribution to journalArticle

Cathepsin L
Central Nervous System

Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for valproic acid and divalproex

Conner, T. M., Nikolian, V. C., Georgoff, P. E., Pai, M. P., Alam, H. B., Sun, D., Reed, R. C. & Zhang, T. Jan 1 2018 In : European Journal of Pharmaceutical Sciences. 111, p. 465-481 17 p.

Research output: Contribution to journalArticle

Drug Design
Valproic Acid
Drug Interactions
Pharmaceutical Preparations
2 Citations

Safety and Tolerability of Intravenous Valproic Acid in Healthy Subjects: A Phase I Dose-Escalation Trial

Georgoff, P. E., Nikolian, V. C., Bonham, T., Pai, M. P., Tafatia, C., Halaweish, I., To, K., Watcharotone, K., Parameswaran, A., Luo, R., Sun, D. & Alam, H. B. Feb 1 2018 In : Clinical Pharmacokinetics. 57, 2, p. 209-219 11 p.

Research output: Contribution to journalArticle

Valproic Acid
Healthy Volunteers
Maximum Tolerated Dose

Smart Nanoparticles Undergo Phase Transition for Enhanced Cellular Uptake and Subsequent Intracellular Drug Release in a Tumor Microenvironment

Ye, G., Jiang, Y., Yang, X., Hu, H., Wang, B., Sun, L., Yang, V. C., Sun, D. & Gao, W. Jan 10 2018 In : ACS Applied Materials and Interfaces. 10, 1, p. 278-289 12 p.

Research output: Contribution to journalArticle

Phase transitions
Pharmaceutical Preparations