David Lombard

  • 7967 Citations
  • 34 Scopus h-Index
1991 …2020

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  • 5 Similar Profiles
Proteins Medicine & Life Sciences
Lysine Medicine & Life Sciences
Acetylation Medicine & Life Sciences
Sirtuins Medicine & Life Sciences
Genomic Instability Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Mammals Medicine & Life Sciences
Genes Medicine & Life Sciences

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Grants 2009 2020

Research Output 1991 2016

1 Citations

Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules

Kumar, S. & Lombard, D. B. 2016 In : F1000Research. 5, F1000 Faculty Rev-406

Research output: Contribution to journalArticle

Invertebrates
Age of Onset
Diptera
Neurodegenerative Diseases
Mammals

Generation and purification of catalytically active recombinant Sirtuin5 (SIRT5) protein

Kumar, S. & Lombard, D. B. 2016 In : Methods in Molecular Biology. 1436, p. 241-257 17 p.

Research output: Contribution to journalArticle

Recombinant Proteins
Neoplasms
Sirtuins
Ketone Bodies
Escherichia coli Proteins
7 Citations

Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples

Guetschow, E. D., Kumar, S., Lombard, D. B. & Kennedy, R. T. Jan 1 2016 In : Analytical and Bioanalytical Chemistry. 408, 3, p. 721-731 11 p.

Research output: Contribution to journalArticle

Microchip Electrophoresis
High-Throughput Screening Assays
Succinate Dehydrogenase
Workflow
Post Translational Protein Processing
11 Citations

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

Xie, Z. , Zhang, D. , Chung, D. , Tang, Z. , Huang, H. , Dai, L. , Qi, S. , Li, J. , Colak, G. , Chen, Y. , Xia, C. , Peng, C. , Ruan, H. , Kirkey, M. , Wang, D. , Jensen, L. M. , Kwon, O. K. , Lee, S. , Pletcher, S. D. , Tan, M. & 7 others Lombard, D. B., White, K. P., Zhao, H., Li, J., Roeder, R. G., Yang, X. & Zhao, Y. Apr 21 2016 In : Molecular Cell. 62, 2, p. 194-206 13 p.

Research output: Contribution to journalArticle

Gene Expression Regulation
Histones
Lysine
3-Hydroxybutyric Acid
Starvation
6 Citations

SIRT3 deacetylates ceramide synthases: Implications for mitochondrial dysfunction and brain injury

Novgorodov, S. A., Riley, C. L., Keffler, J. A., Yu, J., Kindy, M. S., Macklin, W. B., Lombard, D. B. & Gudz, T. I. Jan 22 2016 In : Journal of Biological Chemistry. 291, 4, p. 1957-1973 17 p.

Research output: Contribution to journalArticle

Ceramides
Brain Injuries
Ischemia
Mitochondria
Electron Transport Complex III