Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Polyketide Synthases Medicine & Life Sciences
Streptomyces Medicine & Life Sciences
Polyketides Medicine & Life Sciences
Biosynthesis Chemical Compounds
Biological Products Medicine & Life Sciences
Biosynthetic Pathways Medicine & Life Sciences
Multigene Family Medicine & Life Sciences
Macrolides Medicine & Life Sciences

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Grants 2003 2021

Research Output 1982 2018

Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway

Slocum, S. T., Lowell, A. N., Tripathi, A. N., Smith, J. L. & Sherman, D. H. Jan 1 2018 (Accepted/In press) In : Methods in enzymology.

Research output: Contribution to journalArticle

Bryostatins
Polyketides
Dissection
Biological Products
Enoyl-CoA Hydratase

Halogenase engineering and its utility in medicinal chemistry

Fraley, A. E. & Sherman, D. H. Jun 15 2018 In : Bioorganic and Medicinal Chemistry Letters. 28, 11, p. 1992-1999 8 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
Halogenation
Cracks
Slip forming
Enzymes
1 Citations

Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis article

Newmister, S. A., Li, S., Garcia-Borràs, M., Sanders, J. N., Yang, S., Lowell, A. N., Yu, F., Smith, J. L., Williams, R. M., Houk, K. N. & Sherman, D. H. Apr 1 2018 In : Nature Chemical Biology. 14, 4, p. 345-351 7 p.

Research output: Contribution to journalArticle

Cyclization
Alkaloids
Biological Products
Catalytic Domain
Ions
3 Citations

A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens

Kinnel, R. B., Esquenazi, E., Leao, T., Moss, N., Mevers, E., Pereira, A. R., Monroe, E. A., Korobeynikov, A., Murray, T. F., Sherman, D., Gerwick, L., Dorrestein, P. C. & Gerwick, W. H. May 26 2017 In : Journal of Natural Products. 80, 5, p. 1514-1521 8 p.

Research output: Contribution to journalArticle

Cyanobacteria
Biological Products
Genes
Biosynthesis
Amidinotransferases
2 Citations

A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit

Skiba, M. A., Sikkema, A. P., Moss, N. A., Tran, C. L., Sturgis, R. M., Gerwick, L., Gerwick, W. H., Sherman, D. H. & Smith, J. L. Dec 15 2017 In : ACS chemical biology. 12, 12, p. 3039-3048 10 p.

Research output: Contribution to journalArticle

Bacterial Gene Expression Regulation
Depsipeptides
Polyketides
Protein Conformation
Decarboxylation