Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 10 Similar Profiles
Polyketide Synthases Medicine & Life Sciences
Streptomyces Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Genes Medicine & Life Sciences
Polyketides Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Multigene Family Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences

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Grants 2003 2021

Research Output 1982 2017

Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids

Li, S., Lowell, A. N., Newmister, S. A., Yu, F., Williams, R. M. & Sherman, D. H. May 1 2017 In : Nature Chemical Biology. 13, 5, p. 467-469 3 p.

Research output: Contribution to journalArticle

Cyanobacteria
Cyclization
Alkaloids

Environmental pseudomonads inhibit cystic fibrosis patient-derived Pseudomonas aeruginosa

Chatterjee, P., Davis, E., Yu, F., James, S., Wildschutte, J. H., Wiegmann, D. D., Sherman, D. H., McKay, R. M., LiPuma, J. J. & Wildschutte, H. 2017 In : Applied and Environmental Microbiology. 83, 2, e02701-16

Research output: Contribution to journalArticle

antibiotics
habitat
Cystic Fibrosis
Pseudomonas aeruginosa
soil ecosystem
3 Citations

Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering

Koryakina, I., Kasey, C., McArthur, J. B., Lowell, A. N., Chemler, J. A., Li, S., Hansen, D. A., Sherman, D. H. & Williams, G. J. Jan 20 2017 In : ACS chemical biology. 12, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

Polyketide Synthases
Acyltransferases
Polyketides
Amino Acid Substitution
Substrate Specificity
1 Citations

Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate

Maloney, F. P., Gerwick, L., Gerwick, W. H., Sherman, D. H. & Smith, J. L. Sep 13 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 37, p. 10316-10321 6 p.

Research output: Contribution to journalArticle

1,4-alpha-Glucan Branching Enzyme
Acyl Carrier Protein
Polyketides
Anatomy
Coenzyme A
1 Citations

Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway

Demars, M. D., Sheng, F., Park, S. R., Lowell, A. N., Podust, L. M. & Sherman, D. H. Sep 16 2016 In : ACS Chemical Biology. 11, 9, p. 2642-2654 13 p.

Research output: Contribution to journalArticle

Enzymes
Mixed Function Oxygenases
Macrocyclic Compounds
Tylosin
Macrolides