Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Polyketide Synthases Medicine & Life Sciences
Streptomyces Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Biosynthesis Chemical Compounds
Genes Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Polyketides Medicine & Life Sciences
Substrates Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2003 2021

Research Output 1982 2017

1 Citations

A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens

Kinnel, R. B., Esquenazi, E., Leao, T., Moss, N., Mevers, E., Pereira, A. R., Monroe, E. A., Korobeynikov, A., Murray, T. F., Sherman, D., Gerwick, L., Dorrestein, P. C. & Gerwick, W. H. May 26 2017 In : Journal of Natural Products. 80, 5, p. 1514-1521 8 p.

Research output: Research - peer-reviewArticle

Biological Products
Genes
Cyanobacteria
Biosynthesis
Nitrogen

A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst

Koch, A. A., Hansen, D. A., Shende, V. V., Furan, L. R., Houk, K. N., Jiménez-Osés, G. & Sherman, D. H. 2017 In : Journal of the American Chemical Society. 139, 38, p. 13456-13465 10 p.

Research output: Research - peer-reviewArticle

Catalysts
Substrates
picromycin
Catalytic Domain
Mutation

Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization

Lowell, A. N., Demars, M. D., Slocum, S. T., Yu, F., Anand, K., Chemler, J. A., Korakavi, N., Priessnitz, J. K., Park, S. R., Koch, A. A., Schultz, P. J. & Sherman, D. H. Jun 14 2017 In : Journal of the American Chemical Society. 139, 23, p. 7913-7920 8 p.

Research output: Research - peer-reviewArticle

Polyketide Synthases
Polyketides
Macrolides
Anti-Bacterial Agents
Oxidation

Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii

Li, Z., Du, L., Zhang, W., Zhang, X., Jiang, Y., Liu, K., Men, P., Xu, H., Fortman, J. L., Sherman, D. H., Yu, B., Gao, S. & Li, S. Apr 28 2017 In : Journal of Biological Chemistry. 292, 17, p. 7095-7104 10 p.

Research output: Research - peer-reviewArticle

Fumarates
Biosynthesis
Streptomyces
Polyketide Synthases
Ligases

Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins

Almutairi, M. M., Svetlov, M. S., Hansen, D. A., Khabibullina, N. F., Klepacki, D., Kang, H. Y., Sherman, D. H., Vázquez-Laslop, N., Polikanov, Y. S. & Mankin, A. S. Sep 19 2017 In : Nucleic Acids Research. 45, 16, p. 9573-9582 10 p.

Research output: Research - peer-reviewArticle

Ketolides
Growth
Proteins
methymycin
picromycin