Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Polyketide Synthases Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Streptomyces Medicine & Life Sciences
Genes Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Polyketides Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences
Multigene Family Medicine & Life Sciences

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Grants 2003 2021

Research Output 1982 2016

Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate

Maloney, F. P., Gerwick, L., Gerwick, W. H., Sherman, D. H. & Smith, J. L. Sep 13 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 37, p. 10316-10321 6 p.

Research output: Contribution to journalArticle

1,4-alpha-Glucan Branching Enzyme
Acyl Carrier Protein
Polyketides
Anatomy
Coenzyme A

Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway

Demars, M. D., Sheng, F., Park, S. R., Lowell, A. N., Podust, L. M. & Sherman, D. H. Sep 16 2016 In : ACS Chemical Biology. 11, 9, p. 2642-2654 13 p.

Research output: Contribution to journalArticle

Enzymes
Mixed Function Oxygenases
Macrocyclic Compounds
Tylosin
Macrolides
4 Citations

Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

Park, S. R., Tripathi, A., Wu, J., Schultz, P. J., Yim, I., McQuade, T. J., Yu, F., Arevang, C. J., Mensah, A. Y., Tamayo-Castillo, G., Xi, C. & Sherman, D. H. Feb 16 2016 In : Nature Communications. 7, 10710

Research output: Contribution to journalArticle

Biofilms
Acinetobacter baumannii
Streptomyces
Microbial Drug Resistance
Biological Products

Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase

Skiba, M. A., Sikkema, A. P., Fiers, W. D., Gerwick, W. H., Sherman, D. H., Aldrich, C. C. & Smith, J. L. Dec 16 2016 In : ACS Chemical Biology. 11, 12, p. 3319-3327 9 p.

Research output: Contribution to journalArticle

Polyketide Synthases
Methyltransferases
Catalytic Domain
Acyl Carrier Protein
Polyketides

Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis

Zhang, X., Li, Z., Du, L., Chlipala, G. E., Lopez, P. C., Zhang, W., Sherman, D. H. & Li, S. Dec 28 2016 In : Tetrahedron Letters. 57, 52, p. 5919-5923 5 p.

Research output: Contribution to journalArticle

Streptomyces
Mixed Function Oxygenases
Anti-Bacterial Agents