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  • 15 Similar Profiles
Plasminogen Activator Inhibitor 1 Medicine & Life Sciences
Tissue Plasminogen Activator Medicine & Life Sciences
Vitronectin Medicine & Life Sciences
Plasminogen Activators Medicine & Life Sciences
Proteins Medicine & Life Sciences
Peptide Hydrolases Medicine & Life Sciences
Serpins Medicine & Life Sciences
Urokinase-Type Plasminogen Activator Medicine & Life Sciences

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Grants 1994 2019

Research Output 1983 2017

Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke

Su, E. J., Cao, C., Fredriksson, L., Nilsson, I., Stefanitsch, C., Stevenson, T. K., Zhao, J., Ragsdale, M., Sun, Y. Y., Yepes, M., Kuan, C. Y., Eriksson, U., Strickland, D. K., Lawrence, D. A. & Zhang, L. Oct 1 2017 In : Acta Neuropathologica. 134, 4, p. 585-604 20 p.

Research output: Research - peer-reviewArticle

Platelet-Derived Growth Factor
Tissue Plasminogen Activator
Permeability
Stroke
Platelet-Derived Growth Factor alpha Receptor
1 Citations

Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargo

Bohannon, K. P., Bittner, M. A., Lawrence, D. A., Axelrod, D. & Holz, R. W. 2017 In : Journal of General Physiology. 149, 10, p. 921-934 14 p.

Research output: Research - peer-reviewArticle

Tissue Plasminogen Activator
Plasminogen Activator Inhibitor 1
Proteins
Secretory Vesicles
Fluorescence Microscopy
4 Citations

tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS

Fredriksson, L., Lawrence, D. A. & Medcalf, R. L. Mar 1 2017 In : Seminars in Thrombosis and Hemostasis. 43, 2, p. 154-168 15 p., 02355

Research output: Research - peer-reviewArticle

Plasminogen Activators
Blood-Brain Barrier
Central Nervous System
Neuronal Plasticity
Plasminogen
5 Citations

A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

Motley, M. P., Madsen, D. H., Jürgensen, H. J., Spencer, D. E., Szabo, R., Holmbeck, K., Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H. Mar 3 2016 In : Blood. 127, 9, p. 1085-1096 12 p.

Research output: Research - peer-reviewArticle

CC Chemokines
Chemokine Receptors
Fibrin
Macrophages
Endocytosis

Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1

Pautus, S., Alami, M., Adam, F., Bernadat, G., Lawrence, D. A., De Carvalho, A., Ferry, G., Rupin, A., Hamze, A., Champy, P., Bonneau, N., Gloanec, P., Peglion, J. L., Brion, J. D., Bianchini, E. P. & Borgel, D. Nov 23 2016 In : Scientific Reports. 6, 36462

Research output: Research - peer-reviewArticle

Acetogenins
Plasminogen Activator Inhibitor 1
Biological Products
annonacinone
Thrombelastography