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  • 15 Similar Profiles
Genes Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Multiple Sclerosis Medicine & Life Sciences
Genome Medicine & Life Sciences
Meta-Analysis Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Alleles Medicine & Life Sciences
Population Medicine & Life Sciences

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Grants 2009 2024

Research Output 1998 2017

  • 24279 Citations
  • 50 h-Index
  • 88 Article
  • 6 Review article
  • 4 Comment/debate
  • 2 Letter

A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors

Brænne, I. , Willenborg, C. , Tragante, V. , Kessler, T. , Zeng, L. , Reiz, B. , Kleinecke, M. , Von Ameln, S. , Willer, C. J. , Laakso, M. , Wild, P. S. , Zeller, T. , Wallentin, L. , Franks, P. W. , Salomaa, V. , Dehghan, A. , Meitinger, T. , Samani, N. J. , Asselbergs, F. W. , Erdmann, J. & 1 others Schunkert, H. Dec 1 2017 In : Scientific Reports. 7, 1, 10252

Research output: Research - peer-reviewArticle

Cyclooxygenase 2 Inhibitors
Genes
Coronary Artery Disease
Genome-Wide Association Study
Drug Interactions
7 Citations

Association of rare and common variation in the lipoprotein lipase gene with coronary artery disease

Khera, A. V. , Won, H. H. , Peloso, G. M. , O'Dushlaine, C. , Liu, D. , Stitziel, N. O. , Natarajan, P. , Nomura, A. , Emdin, C. A. , Gupta, N. , Borecki, I. B. , Asselta, R. , Duga, S. , Merlini, P. A. , Correa, A. , Kessler, T. , Wilson, J. G. , Bown, M. J. , Hall, A. S. , Braund, P. S. & 24 others Carey, D. J., Murray, M. F., Kirchner, H. L., Leader, J. B., Lavage, D. R., Manus, J. N., Hartzel, D. N., Samani, N. J., Schunkert, H., Marrugat, J., Elosua, R., McPherson, R., Farrall, M., Watkin, H., Lander, E. S., Rader, D. J., Danesh, J., Ardissino, D., Gabriel, S., Willer, C., Abecasis, G. R., Saleheen, D., Dewey, F. E. & Kathiresan, S. Mar 7 2017 In : JAMA - Journal of the American Medical Association. 317, 9, p. 937-946 10 p.

Research output: Research - peer-reviewArticle

Lipoprotein Lipase
Coronary Artery Disease
Genes
Mutation
Triglycerides

Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

Brænne, I. , Zeng, L. , Willenborg, C. , Tragante, V. , Kessler, T. , Willer, C. J. , Laakso, M. , Wallentin, L. , Franks, P. W. , Salomaa, V. , Dehghan, A. , Meitinger, T. , Samani, N. J. , Asselbergs, F. W. , Erdmann, J. , Schunkert, H. , Deloukas, P. , Kanoni, S. , Willenborg, C. , Farrall, M. & 198 others Assimes, T. L., Thompson, J. R., Ingelsson, E., Saleheen, D., Erdmann, J., Goldstein, B. A., Stirrups, K., König, I. R., Cazier, J. B., Johansson, Å., Hall, A. S., Lee, J. Y., Willer, C. J., Chambers, J. C., Esko, T., Folkersen, L., Goel, A., Grundberg, E., Havulinna, A. S., Ho, W. K., Hopewell, J. C., Eriksson, N., Kleber, M. E., Kristiansson, K., Lundmark, P., Lyytikäinen, L. P., Rafelt, S., Shun, D., Strawbridge, R. J., Thorleifsson, G., Tikkanen, E., Van Zuydam, N., Voight, B. F., Waite, L. L., Zhang, W., Zieg, A., Absher, D., Altshuler, D., Balmforth, A. J., Barroso, I., Braund, P. S., Burgdorf, C., Claudi-Boehm, S., Cox, D., Dimitriou, M., Do, R., Doney, A. S. F., El Mokhtari, N. E., Eriksson, P., Fischer, K., Fontanillas, P., Franco-Cereceda, A., Gigante, B., Groop, L., Gustafsson, S., Hager, J., Hallmans, G., Han, B. G., Ehunt, S., Kang, H. M., Illig, T., Kessler, T., Knowles, J. W., Kolovou, G., Kuusisto, J., Langenberg, C., Langford, C., Leander, K., Lokki, M. L., Lundmark, A., McCarthy, M. I., Meisinger, C., Melander, O., Mihailov, E., Maouche, S., Morris, A. D., Müller-Nurasyid, M., Nikus, K., Peden, J. F., Rayner, N. W., Rasheed, A., Rosinger, S., Rubin, D., Rumpf, M. P., Schäfer, A., Sivananthan, M., Song, C., Stewart, A. F. R., Tan, S. T., Thorgeirsson, G., Van Der Schoot, C. E., Wagner, P. J., Wells, G. A., Wild, P. S., Yang, T. P., Amouyel, P., Arveiler, D., Basart, H., Boehnke, M., Boerwinkle, E., Brambilla, P., Cambien, F., Cupples, A. L., De Faire, U., Dehghan, A., Diemert, P., Epstein, S. E., Evans, A., Ferrario, M. M., Ferrières, J., Gauguier, D., Go, A. S., Goodall, A. H., Gudnason, V., Hazen, S. L., Holm, H., Iribarren, C., Jang, Y., Kähönen, M., Kee, F., Kim, H. S., Klopp, N., Koenig, W., Kratzer, W., Kuulasmaa, K., Laakso, M., Laaksonen, R., Lee, J. Y., Lind, L., Ouwehand, W. H., Parish, S., Park, J. E., Pedersen, N. L., Peters, A., Quertermous, T., Rader, D. J., Salomaa, V., Schadt, E., Shah, S. H., Sinisalo, J., Stark, K., Stefansson, K., Trégouët, D. A., Virtamo, J., Wallentin, L., Wareham, N., Zimmermann, M. E., Nieminen, M. S., Hengsten, C., Sandhu, M. S., Pastinen, T., Syvänen, A. C., Hovingh, G. K., Dedoussis, G., Franks, P. W., Lehtimäki, T., Metspalu, A., Zalloua, P. A., Siegbahn, A., Schreiber, S., Ripatti, S., Blankenberg, S. S., Perola, M., Clarke, R., Oboehm, B., O’Donnell, C., Reilly, M. P., März, W., Collins, R., Kathiresan, S., Hamsten, A., Kooner, J. S., Thorsteinsdottir, U., Danesh, J., Palmer, C. N. A., Roberts, R., Watkins, H., Schunkert, H., Samani, N. J., Assimes, T. L., Boerwinkle, E., Erdmann, J., Hall, A., Hengstenberg, C., Kathiresan, S., König, I. R., Laaksonen, R., McPherson, R., Reilly, M. P., Samani, N. J., Schunkert, H., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, MuTHER Consortium & Wellcome Trust Case Control Consortium Aug 1 2017 In : PLoS ONE. 12, 8, e0182999

Research output: Research - peer-reviewArticle

acetates
genomics
loci
coronary artery disease
Coronary Artery Disease

Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels

Zhou, W., Fritsche, L. G., Das, S., Zhang, H., Nielsen, J. B., Holmen, O. L., Chen, J., Lin, M., Elvestad, M. B., Hveem, K., Abecasis, G. R., Kang, H. M. & Willer, C. J. Dec 1 2017 In : Genetic Epidemiology. 41, 8, p. 744-755 12 p.

Research output: Research - peer-reviewArticle

Genotype
Population
Genome
Haplotypes
Gene Frequency
1 Citations

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Kraja, A. T. , Cook, J. P. , Warren, H. R. , Surendran, P. , Liu, C. , Evangelou, E. , Manning, A. K. , Grarup, N. , Drenos, F. , Sim, X. , Smith, A. V. , Amin, N. , Blakemore, A. I. F. , Bork-Jensen, J. , Brandslund, I. , Farmaki, A. E. , Fava, C. , Ferreira, T. , Herzig, K. H. , Giri, A. & 124 others Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A. M., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Rice, K., Richard, M. A., Smith, J. A., Southam, L., Stančáková, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulaki, I., Varga, T. V., Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., De Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dörr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L., Hallmans, G., Hansen, T., Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M. R., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, R. J. F., Laakso, M., McCarthy, M. I., Melander, O., Mohlke, K. L., Morris, A. P., Palmer, C. N. A., Pedersen, O., Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., Van Der Harst, P., Van Der Meer, P., Van Duijn, C. M., Vergnaud, A. C., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-Cheh, C., Munroe, P. B., Howson, J. M. M., The Understanding Society Scientific Group & behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group Oct 1 2017 In : Circulation: Cardiovascular Genetics. 10, 5, e001778

Research output: Research - peer-reviewArticle

Meta-Analysis
Blood Pressure
Nucleotides
Genome
Genes