Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Neoplasms Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Glutamine Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Glucose Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Metabolic Networks and Pathways Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2004 2017

Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis

Wahl, D. R., Dresser, J., Wilder-Romans, K., Parsels, J. D., Zhao, S. G., Davis, M., Zhao, L., Kachman, M., Wernisch, S., Burant, C. F., Morgan, M. A., Feng, F. Y., Speers, C., Lyssiotis, C. A. & Lawrence, T. S. Feb 15 2017 In : Cancer Research. 77, 4, p. 960-970 11 p.

Research output: Contribution to journalArticle

Glioblastoma
NADP
Radiotherapy
Neoplasms
Isocitrate Dehydrogenase

Inhibiting oxidative phosphorylation in vivo restrains Th17 effector responses and ameliorates murine colitis

Franchi, L. , Lyssiotis, C. A. , Opipari, A. W. & 18 others Monteleone, I., Hao, L. Y., Spahr, M. A., Zhao, W., Liu, X., Demock, K., Kulkarni, A., Lesch, C. A., Sanchez, B., Carter, L., Marafini, I., Hu, X., Mashadova, O., Yuan, M., Asara, J. M., Singh, H., Monteleone, G. & Glick, G. D. Apr 1 2017 In : Journal of Immunology. 198, 7, p. 2735-2746 12 p.

Research output: Contribution to journalArticle

Oxidative Phosphorylation
Colitis
Th17 Cells
Lymphocytes
T-Lymphocytes
1 Citations

Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer

Meyer, K. A., Neeley, C. K., Baker, N. A., Washabaugh, A. R., Flesher, C. G., Nelson, B. S., Frankel, T. L., Lumeng, C. N., Lyssiotis, C. A., Wynn, M. L., Rhim, A. D. & O'Rourke, R. W. Sep 1 2016 In : Biochemistry and Biophysics Reports. 7, p. 144-149 6 p.

Research output: Contribution to journalArticle

Glutamine
Pancreatic Neoplasms
Adipocytes
Cell Proliferation
Neoplasms

Erratum: Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers (Proceedings of the National Academy of Sciences of the United States of America (2016) 113 (1778-1783) DOI:10.1073/pnas.1521548113)

Mullarky, E., Lucki, N. C., Zavareh, R. B., Anglin, J. L., Gomes, A. P., Nicolay, B. N., Wong, J. C. Y., Christen, S., Takahashi, H., Singh, P. K., Blenis, J., Warren, J. D., Fendt, S. M., Asara, J. M., DeNicola, G. M., Lyssiotis, C. A., Lairson, L. L. & Cantley, L. C. Mar 15 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 11, p. E1585

Research output: Contribution to journalComment/debate

2 Citations

Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer

Lien, E. C., Lyssiotis, C. A., Juvekar, A., Hu, H., Asara, J. M., Cantley, L. C. & Toker, A. May 1 2016 In : Nature Cell Biology. 18, 5, p. 572-578 7 p.

Research output: Contribution to journalArticle

Glutathione
Breast Neoplasms
Neoplasms
Up-Regulation
Mutation