Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 17 Similar Profiles
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Glucose Medicine & Life Sciences
Growth Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Cells Chemical Compounds
Adenocarcinoma Medicine & Life Sciences

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Grants 2015 2022

Research Output 2004 2017

A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers

Bollong, M. J., Pietilä, M., Pearson, A. D., Sarkar, T. R., Ahmad, I., Soundararajan, R., Lyssiotis, C. A., Mani, S. A., Schultz, P. G. & Lairson, L. L. Nov 14 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 46, p. E9903-E9912

Research output: Research - peer-reviewArticle

Vimentin
Neoplasms
Growth
Epithelial-Mesenchymal Transition
Intermediate Filaments
3 Citations

Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer

Halbrook, C. J. & Lyssiotis, C. A. Jan 9 2017 In : Cancer Cell. 31, 1, p. 5-19 15 p.

Research output: Research - peer-reviewReview article

Pancreatic Neoplasms
Therapeutics
Tumor Microenvironment
Metabolic Networks and Pathways
Oncogenes

Erratum: MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer (Cancer Cell (2017) 32(1) (71–87.e7) (S1535610817302544) (10.1016/j.ccell.2017.06.004))

Shukla, S. K. , Purohit, V. , Mehla, K. , Gunda, V. , Chaika, N. V. , Vernucci, E. , King, R. J. , Abrego, J. , Goode, G. D. , Dasgupta, A. , Illies, A. L. , Gebregiworgis, T. , Dai, B. , Augustine, J. J. , Murthy, D. , Attri, K. S. , Mashadova, O. , Grandgenett, P. M. , Powers, R. , Ly, Q. P. & 17 others Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Serkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P. K. Sep 11 2017 In : Cancer Cell. 32, 3, 1 p.

Research output: Research - peer-reviewComment/debate

gemcitabine
Pancreatic Neoplasms
Names
Glucose
Neoplasms
3 Citations

Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis

Wahl, D. R., Dresser, J., Wilder-Romans, K., Parsels, J. D., Zhao, S. G., Davis, M., Zhao, L., Kachman, M., Wernisch, S., Burant, C. F., Morgan, M. A., Feng, F. Y., Speers, C., Lyssiotis, C. A. & Lawrence, T. S. Feb 15 2017 In : Cancer Research. 77, 4, p. 960-970 11 p.

Research output: Research - peer-reviewArticle

Glioblastoma
NADP
Therapeutics
Radiotherapy
Neoplasms
3 Citations

Inhibiting oxidative phosphorylation in vivo restrains Th17 effector responses and ameliorates murine colitis

Franchi, L. , Monteleone, I. , Hao, L. Y. , Spahr, M. A. , Zhao, W. , Liu, X. , Demock, K. , Kulkarni, A. , Lesch, C. A. , Sanchez, B. , Carter, L. , Marafini, I. , Hu, X. , Mashadova, O. , Yuan, M. , Asara, J. M. , Singh, H. , Lyssiotis, C. A. , Monteleone, G. , Opipari, A. W. & 1 others Glick, G. D. Apr 1 2017 In : Journal of Immunology. 198, 7, p. 2735-2746 12 p.

Research output: Research - peer-reviewArticle

Oxidative Phosphorylation
Colitis
Th17 Cells
Lymphocytes
T-Lymphocytes