Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Molecules Chemical Compounds
Apoptosis Medicine & Life Sciences
Cell Line Medicine & Life Sciences
X-Linked Inhibitor of Apoptosis Protein Medicine & Life Sciences
Caspases Medicine & Life Sciences
Mitochondria Medicine & Life Sciences

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Grants 2003 2022

Research Output 1994 2017

  • 2839 Citations
  • 30 Scopus h-Index
  • 64 Article
  • 6 Review article
  • 2 Comment/debate
  • 1 Chapter
Polycomb Repressive Complex 2
Embryonic Development
Proteins
Epigenomics
Heterografts

Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor

Zhao, Y., Bai, L., Liu, L., McEachern, D., Stuckey, J. A., Meagher, J. L., Yang, C. Y., Ran, X., Zhou, B., Hu, Y., Li, X., Wen, B., Zhao, T., Li, S., Sun, D. & Wang, S. May 11 2017 In : Journal of Medicinal Chemistry. 60, 9, p. 3887-3901 15 p.

Research output: Contribution to journalArticle

Proteins
Leukemia
Triple Negative Breast Neoplasms
Heterografts
Pharmacokinetics
2 Citations

Targeted degradation of BET proteins in triple-negative breast cancer

Bai, L. , Zhou, B. , Yang, C. Y. , Ji, J. , McEachern, D. , Przybranowski, S. , Jiang, H. , Hu, J. , Xu, F. , Zhao, Y. , Liu, L. , Fernandez-Salas, E. , Xu, J. , Dou, Y. , Wen, B. , Sun, D. , Meagher, J. , Stuckey, J. , Hayes, D. F. , Li, S. & 2 others Ellis, M. J. & Wang, S. May 1 2017 In : Cancer Research. 77, 9, p. 2476-2487 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Proteolysis
Apoptosis
Genes
Down-Regulation
2 Citations

Targeting the MDM2-p53 protein-protein interaction for new cancer therapy: Progress and challenges

Wang, S., Zhao, Y., Aguilar, A., Bernard, D. & Yang, C. Y. May 1 2017 In : Cold Spring Harbor Perspectives in Medicine. 7, 5, a026245

Research output: Contribution to journalReview article

Neoplasms
Proteins
Molecules
Clinical Trials
Cecal Neoplasms
1 Citations

Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors

Yang, C. Y., Phillips, J. G., Stuckey, J. A., Bai, L., Sun, H., Delproposto, J., Brown, W. C. & Chinnaswamy, K. Dec 8 2016 In : ACS Medicinal Chemistry Letters. 7, 12, p. 1092-1096 5 p.

Research output: Contribution to journalArticle

Complement Factor D
Hydrogen
Amides
Alternative Complement Pathway
Cape Verde