Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 20 Similar Profiles
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Molecules Chemical Compounds
Growth Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Ligands Chemical Compounds
X-Linked Inhibitor of Apoptosis Protein Medicine & Life Sciences

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Grants 2003 2022

Research Output 1994 2017

  • 2895 Citations
  • 30 Scopus h-Index
  • 64 Article
  • 6 Review article
  • 2 Comment/debate
  • 1 Chapter
Polycomb Repressive Complex 2
Embryonic Development
Proteins
Epigenomics
Heterografts

Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor

Zhao, Y., Bai, L., Liu, L., McEachern, D., Stuckey, J. A., Meagher, J. L., Yang, C. Y., Ran, X., Zhou, B., Hu, Y., Li, X., Wen, B., Zhao, T., Li, S., Sun, D. & Wang, S. May 11 2017 In : Journal of Medicinal Chemistry. 60, 9, p. 3887-3901 15 p.

Research output: Research - peer-reviewArticle

Proteins
indole
Leukemia
Triple Negative Breast Neoplasms
Heterografts
5 Citations

Targeted degradation of BET proteins in triple-negative breast cancer

Bai, L. , Zhou, B. , Yang, C. Y. , Ji, J. , McEachern, D. , Przybranowski, S. , Jiang, H. , Hu, J. , Xu, F. , Zhao, Y. , Liu, L. , Fernandez-Salas, E. , Xu, J. , Dou, Y. , Wen, B. , Sun, D. , Meagher, J. , Stuckey, J. , Hayes, D. F. , Li, S. & 2 others Ellis, M. J. & Wang, S. May 1 2017 In : Cancer Research. 77, 9, p. 2476-2487 12 p.

Research output: Research - peer-reviewArticle

Triple Negative Breast Neoplasms
Proteolysis
Apoptosis
Genes
Down-Regulation
4 Citations

Targeting the MDM2-p53 protein-protein interaction for new cancer therapy: Progress and challenges

Wang, S., Zhao, Y., Aguilar, A., Bernard, D. & Yang, C. Y. May 1 2017 In : Cold Spring Harbor Perspectives in Medicine. 7, 5, a026245

Research output: Research - peer-reviewReview article

Neoplasms
Proteins
Therapeutics
Molecules
Clinical Trials
2 Citations

Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors

Yang, C. Y., Phillips, J. G., Stuckey, J. A., Bai, L., Sun, H., Delproposto, J., Brown, W. C. & Chinnaswamy, K. Dec 8 2016 In : ACS Medicinal Chemistry Letters. 7, 12, p. 1092-1096 5 p.

Research output: Research - peer-reviewArticle

Complement Factor D
Hydrogen bonds
Hydrogen
Amides
Assays