Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 1 Similar Profiles
Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Small Cell Lung Carcinoma Medicine & Life Sciences
Clinical Trials Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Pyrroles Medicine & Life Sciences

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Grants 2014 2019

Research Output 2012 2015

  • 282 Citations
  • 9 Scopus h-Index
  • 8 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article

Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels

Lu, J., Aguilar, A., Zou, B., Bao, W., Koldas, S., Shi, A., Desper, J., Wangemann, P., Xie, X. S. & Hua, D. H. Apr 28 2015 In : Bioorganic and Medicinal Chemistry. 23, 17, p. 5985-5998 14 p.

Research output: Contribution to journalArticle

Terpenes
Calcium Channels
Endothelin-1
Vasoconstriction
Gerbillinae
80 Citations

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for cancer treatment

Zhao, Y., Aguilar, A., Bernard, D. & Wang, S. Feb 12 2015 In : Journal of Medicinal Chemistry. 58, 3, p. 1038-1052 15 p.

Research output: Contribution to journalReview article

Clinical Trials
Neoplasms
Proteins
18 Citations

BM-1197: A novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo

Bai, L., Chen, J., McEachern, D., Liu, L., Zhou, H., Aguilar, A. & Wang, S. Jun 5 2014 In : PLoS One. 9, 6, e99404

Research output: Contribution to journalArticle

Neoplasms
Small Cell Lung Carcinoma
Apoptosis
Proteins
bcl-2-Associated X Protein
9 Citations

Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles

Aguilar, A., Sun, W., Liu, L., Lu, J., McEachern, D., Bernard, D., Deschamps, J. R. & Wang, S. Dec 26 2014 In : Journal of Medicinal Chemistry. 57, 24, p. 10486-10496 11 p.

Research output: Contribution to journalArticle

Cyclization
Neoplasms
Proteins
Heterografts
51 Citations

SAR405838: An optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression

Wang, S. , Stuckey, J. A. , Meagher, J. L. , Bai, L. , Lu, J. , Aguilar, A. & 16 others Sun, W., Zhao, Y., McEachern, D., Meaux, I., Barrière, C., Liu, L., Hoffman-Luca, C. G., Shangary, S., Yu, S., Bernard, D., Dos-Santos, O., Besret, L., Guerif, S., Pannier, P., Gorge-Bernat, D. & Debussche, L. Oct 15 2014 In : Cancer Research. 74, 20, p. 5855-5865 11 p.

Research output: Contribution to journalArticle

Neoplasms
Heterografts
Leukemia
Apoptosis
Proteins