hnRNPU/TrkB defines a chromatin accessibility checkpoint for liver injury and NASH pathogenesis.

Xuelian Xiong, Tongyu Liu, Lin Mi, Henry Kuang, Zhimin Chen, Siming Li, Jiandie Lin

2019, Hepatology - Article

Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis

X Xiong, H Kuang, S Ansari, T Liu, J Gong, S Wang, Xuyun Zhao, Yewei Ji, C Li, L Guo, L Zhou, Z Chen, P Leon-Mimila, MT Chung, Katsuo Kurabayashi, J Opp, F Campos-Pérez, H Villamil-Ramírez, S Canizales-Quinteros, R Lyons, CN Lumeng, B Zhou, Ling Qi, A Huertas-Vazquez, AJ Lusis, XZS Xu, Siming Li, Y Yu, JZ Li, Jiandie Lin

2019, Molecular Cell - Article

Regulation of hepatic autophagy by stress-sensing transcription factor CREBH

H Kim, D Williams, Y Qiu, Z Song, Z Yang, V Kimler, A Goldberg, K Zhang, Z Yang, X Chen, L Wang, D Fang, Jiandie Lin

2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology - Article

Brown fat activation mitigates alcohol-induced liver steatosis and injury in mice

H Shen, L Jiang, Jiandie Lin, M Bishr Omary, Liangyou Rui

2019, Journal of Clinical Investigation - Article

GPNMB: expanding the code for liver–fat communication

H Kuang, Jiandie Lin

2019, Nature Metabolism - Article

The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation

Q Wang, VP Sharma, H Shen, Y Xiao, Q Zhu, X Xiong, L Guo, L Jiang, K Ohta, Siming Li, H Shi, Liangyou Rui, Jiandie Lin

2019, Nature Metabolism - Article

Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi

X Xiong, Q Wang, S Wang, J Zhang, T Liu, L Guo, Y Yu, Jiandie Lin

2019, Molecular Metabolism - Article

Function and mechanism of long noncoding RNAs in adipocyte biology

L Sun, Jiandie Lin

2019, Diabetes - Article

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN

B Liu, S Jiang, X Li, X Xiong, M Zhu, D Li, L Zhao, L Qian, L Zhai, J Li, H Lu, S Sun, Jiandie Lin, Y Lu, M Tan

2018, Nature Communications - Article

Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis

Xuyun Zhao, X Xiong, T Liu, L Mi, X Peng, C Rui, L Guo, Siming Li, X Li, Jiandie Lin

2018, Nature Communications - Article

Erratum: PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ (Cell Stem Cell (2018) 23(2) (193–209.e5), (S1934590918302911) (10.1016/j.stem.2018.06.009))

B Yu, L Huo, Y Liu, P Deng, J Szymanski, J Li, X Luo, C Hong, Jiandie Lin, CY Wang

2018, Cell Stem Cell - Article

PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ

B Yu, L Huo, Y Liu, P Deng, J Szymanski, J Li, X Luo, C Hong, Jiandie Lin, CY Wang

2018, Cell Stem Cell - Article

The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic health

Xuyun Zhao, Siming Li, JL DelProposto, T Liu, L Mi, C Porsche, X Peng, Carey Lumeng, Jiandie Lin

2018, Molecular Metabolism - Article

KDM4B protects against obesity and metabolic dysfunction

Y Cheng, Q Yuan, L Vergnes, X Rong, JY Youn, J Li, Y Yu, W Liu, H Cai, Jiandie Lin, P Tontonoz, C Hong, K Reue, CY Wang

2018, Proceedings of the National Academy of Sciences of the United States of America - Article

An OLTAM system for analysis of brown/beige fat thermogenic activity

DI Kim, J Liao, MP Emont, MJ Park, H Jun, SK Ramakrishnan, Jiandie Lin, Yatrik Shah, MB Omary, Jun Wu, Bishr Omary

2018, International Journal of Obesity - Article

NRG1-Fc improves metabolic health via dual hepatic and central action

P Zhang, H Kuang, Y He, SO Idiga, Siming Li, Z Chen, Z Yang, X Cai, K Zhang, MJ Potthoff, Y Xu, Jiandie Lin

2018, JCI insight - Article

The SWI/SNF chromatin-remodeling factors BAF60a, b, and c in nutrient signaling and metabolic control

RR Wang, R Pan, W Zhang, J Fu, Jiandie Lin, ZX Meng

2018, Protein and Cell - Article

Bmal1 in perivascular adipose tissue regulates resting-phase blood pressure through transcriptional regulation of angiotensinogen

Lin Chang, W Xiong, X Zhao, Yanbo Fan, Yanhong Guo, Minerva Garcia-Barrio, Jifeng Zhang, Z Jiang, Jiandie Lin, Yuqing Chen

2018, Circulation - Article

Uncoupling exercise bioenergetics from systemic metabolic homeostasis by conditional inactivation of Baf60 in skeletal muscle

ZX Meng, W Tao, J Sun, Q Wang, L Mi, Jiandie Lin

2018, Diabetes - Article

MitoNEET in perivascular adipose tissue blunts atherosclerosis under mild cold condition in mice

W Xiong, X Zhao, Minerva Garcia-Barrio, Jifeng Zhang, Jiandie Lin, Y Eugene Chen, Z Jiang, Lin Chang, Yuqing Chen, Yanbo Fan

2017, Frontiers in Physiology - Article

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