A novel heat shock protein 90 inhibitor potently targets adrenocortical carcinoma tumor suppression

Ton Wang, Chitra Subramanian, Brian SJ Blagg, Mark Cohen

2020, Surgery - Article

Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer

Ton Wang, Chitra Subramanian, Minzhi Yu, Peter T White, Rui Kuai, Jaquelyn Sanchez, James Moon, Barbara N Timmermann, Anna Schwendeman, Mark Cohen

2019, Surgery - Article

Hypoxia-Inducible Factor (HIF)-1α Promotes Inflammation and Injury Following Aspiration-Induced Lung Injury in Mice

Madathilparambil V Suresh, Sanjay Balijepalli, Boya Zhang, Vikas Vikram Singh, Samantha Swamy, Sreehari Panicker, Vladislov A Dolgachev, Chitra Subramanian, Sadeesh K Ramakrishnan, Bivin Thomas, Tejeshwar C Rao, Matthew Delano, David Machado-Aranda, Yatrik Shah, Krishnan Raghavendran

2019 - Proceeding

The Role of Deferoxamine in Irradiated Breast Reconstruction: A Study of Oncologic Safety.

Jeremy V Lynn, Kevin M Urlaub, Kavitha Ranganathan, Alexis Donneys, Noah S Nelson, Chitra Subramanian, Mark Cohen, Steven Buchman

2019, Plastic & Reconstructive Surgery - Article

Over expression of DNA damage and cell cycle dependent proteins are associated with poor survival in patients with adrenocortical carcinoma

Chitra Subramanian, Mark Cohen

2019, Surgery - Article

Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor

Anuj Khandelwal, Caitlin N Kent, Maurie Balch, Shuxia Peng, Sanket J Mishra, Junpeng Deng, Victor W Day, Weiya Liu, Chitra Subramanian, Mark Cohen, Jeffery M Holzbeierlein, Robert Matts, Brian SJ Blagg

2018, Nature Communications - Article

Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal

Chitra Subramanian, Peter T White, Rui Kuai, Avinaash Kalidindi, Valerie P Castle, James Moon, Barbara N Timmermann, Anna Schwendeman, Mark Cohen

2018, Surgery - Article

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-κB activation

Chitra Subramanian, Patrick T Grogan, Valerie Opipari, Barbara N Timmermann, Mark Cohen

2018, Oncotarget - Article

Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells

Chitra Subramanian, KJ Kovatch, MW Sim, G Wang, Mark Prince, Thomas Carey, R Davis, BSJ Blagg, Mark Cohen

2017, Neoplasia - Article

Synthetic high-density lipoprotein nanodisks for targeted withalongolide delivery to adrenocortical carcinoma

Rui Kuai, Chitra Subramanian, Peter T White, Barbara N Timmermann, James Moon, Mark Cohen, Anna Schwendeman

2017, International Journal of Nanomedicine - Article

Cytosolic Ku70 regulates Bax-mediated cell death

Manila Hada, Chitra Subramanian, Philip Andrews, Roland Kwok

2016, Tumor Biology - Article

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors

Katherine M Byrd, Chitra Subramanian, Jacqueline Sanchez, Hashim F Motiwala, Weiya Liu, Mark Cohen, Jeffrey Holzbeierlein, Brian SJ Blagg

2016, Chemistry - A European Journal - Article

Effects of peritumoral nanoconjugated cisplatin on laryngeal cancer stem cells

Michael W Sim, Patrick T Grogan, Chitra Subramanian, Carol Bradford, Thomas Carey, M Laird Forrest, Mark Prince, Mark Cohen

2016, The Laryngoscope - Article

Synthetic high-density lipoprotein nanoparticles: A novel therapeutic strategy for adrenocortical carcinomas

Chitra Subramanian, Rui Kuai, Qing Zhu, Peter White, James Moon, Anna Schwendeman, Mark Cohen

2016, Surgery - Article

Natural Withanolides in the Treatment of Chronic Diseases

Peter T White, Chitra Subramanian, Hashim F Motiwala, Mark Cohen

2016, Adv Exp Med Biol - Article

Novel HSP90 inhibitors effectively target functions of thyroid cancer stem cell preventing migration and invasion

Peter T White, Chitra Subramanian, Qing Zhu, Huaping Zhang, Huiping Zhao, Robert Gallagher, Barbara N Timmermann, Brian SJ Blagg, Mark Cohen

2016, Surgery - Article

The therapeutic potential of Physalis longifolia against various carcinomas

Robert J Gallagher, Chitra Subramanian, Patrick T Grogan, Kelly Kindscher, Cong-Mei Cao, Huaping Zhang, Mark Cohen, Barbara N Timmermann

2015, PharmaNutrition - Article

Withanolides are Potent Novel Targeted Therapeutic Agents Against Adrenocortical Carcinomas

Chitra Subramanian, Huaping Zhang, Robert Gallagher, Gary Hammer, Barbara Timmermann, Mark Cohen

2014, World Journal of Surgery - Article

Triazole containing novobiocin and biphenyl amides as Hsp90 C-terminal inhibitors

Huiping Zhao, Jessica A Hall, Douglas Brown, Eileen Brandes, Joseph Bazzill, Patrick T Grogan, Chitra Subramanian, George Vielhauer, Mark Cohen, Brian SJ Blagg

2014, MedChemComm - Article

Antiproliferative withanolides from Datura wrightii.

Huaping Zhang, Joseph Bazzill, Robert J Gallagher, Chitra Subramanian, Patrick T Grogan, Victor W Day, Kelly Kindscher, Mark Cohen, Barbara N Timmermann

2013, Journal of Natural Products - Article

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