IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

FJ Núñez, Sriram Venneti, MG Savelieff, MZ Guo, V Gorbunova, Carl Koschmann, ME Figueroa, N Kamran, CJ Herting, Costas Lyssiotis, R Patel, M Edwards, Mats Ljungman, Maria Castro, Lili Zhao, R Tagett, A Meeker, Pedro Lowenstein, S Haase, L Zhang, DM Kremer, FM Mendez, AA Calinescu, S Carney, M Saxena, P Kadiyala, JL Ross, D Hambardzumyan, J Brosnan-Cashman, T Qin, L Jones, MB Garcia-Fabiani, Maureen Sartor, S Hervey-Jumper, MS Alghamri

2019, Science Translational Medicine - Article

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme

D Altshuler, M Yu, R Kuai, JJ Moon, N Kamran, R Doherty, Anna Schwendeman, P Kadiyala, D Li, Maria Castro, FM Nunez, Pedro Lowenstein, M Edwards

2019, ACS Nano - Article

Evaluation of biomarkers in glioma by immunohistochemistry on paraffin- embedded 3D glioma neurosphere cultures

FM Mendez, J Pardo, Pedro Lowenstein, FJ Núñez, M Edwards, MB Garcia-Fabiani, Maria Castro

2019, Journal of Visualized Experiments - Article

Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy

M Chandran, Maria Castro, N Kamran, Pedro Lowenstein

2018, Clinical Immunology - Article

Evolutionary basis of a new gene- and immune-therapeutic approach for the treatment of malignant brain tumors: from mice to clinical trials for glioma patients

Pedro Lowenstein, Maria Castro

2018, Clinical Immunology - Article

Melanoma induced immunosuppression is mediated by hematopoietic dysregulation

Y Li, M Edwards, P Kadiyala, MS Alghamri, Pedro Lowenstein, Henry Appelman, N Kamran, M Sierra, Maria Castro

2018, OncoImmunology - Article

Native chromatin immunoprecipitation using murine brain tumor neurospheres

FM Mendez, Pedro Lowenstein, FJ Núñez, Maria Castro, RI Zorrilla-Veloz

2018, Journal of Visualized Experiments - Article

Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab

Henry Appelman, Pedro Lowenstein, PR Löwenstein, Maria Castro, P Kadiyala, VN Yadav, D Altshuler, Carl Koschmann, P Dunn, D Zamler, A Comba

2018, Neuro-Oncology - Article

Dual activation of Toll-like receptors 7 and 9 impairs the efficacy of antitumor vaccines in murine models of metastatic breast cancer

E Bal de Kier Joffé, S Klein, M Candolfi, Maria Castro, A De Laurentiis, MA Moreno Ayala, A Seilicovich, C Caruso, M Imsen, MF Gottardo, MS Gori, AJ Nicola Candia, G Salamone

2017, Journal of Cancer Research and Clinical Oncology - Article

Single vs. combination immunotherapeutic strategies for glioma

Pedro Lowenstein, M Candolfi, Y Mineharu, Carl Koschmann, D Shah, M Chandran, Maria Castro, VN Yadav, AS Asad

2017, Expert Opinion on Biological Therapy - Article

Survival and proliferation of neural progenitor-derived glioblastomas under hypoxic stress is controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism

P Kadiyala, R Doherty, Anda-Alexandra Calinescu, Pedro Lowenstein, D Tran, M Srikanth, DB Zamler, VN Yadav, Maria Castro, E Carballo

2017, Clinical Cancer Research - Article

Mutated chromatin regulatory factors as tumor drivers in cancer

Pedro Lowenstein, Maria Castro, JA Brosnan-Cashman, FJ Nunez, Carl Koschmann, F Mendez, AK Meeker

2017, Cancer Research - Article

Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

N Kamran, Pedro Lowenstein, M Candolfi, P Kadiyala, Y Li, MA Moreno-Ayala, N Raja, D Shah, Maria Castro, M Saxena

2017, Molecular Therapy - Article

Matrix metalloproteinase activity in infections by an encephalitic virus, mouse adenovirus type 1

Katherine Spindler, KE Carnahan, Maria Castro, SL Ashley, L Castro-Jorge, P Kadiyala, MT Stier, R Doherty, CD Pretto, TH Hsu, Pedro Lowenstein

2017, Journal of Virology - Article

Recent advances and future of immunotherapy for glioblastoma

Pedro Lowenstein, Anda-Alexandra Calinescu, M Candolfi, Y Mineharu, Carl Koschmann, FJ Nunez, M Chandran, Maria Castro, N Kamran, AS Asad

2016, Expert Opinion on Biological Therapy - Article

Multiple expressed endogenous glioma epitopes as novel vaccines for gliomas

Maria Castro, Pedro Lowenstein

2016, Clinical Cancer Research - Article

First detection of natural infection of Aedes aegypti with Zika virus in Brazil and throughout South America.

Patrícia Brasil, Myrna Bonaldo, Maria Castro, Ieda Ribeiro, Stéphanie Campos, Ricardo Lourenço-de-Oliveira, Rosilainy Fernandes, Anielly Ferreira-de-Brito, Rafaella Miranda, Keli Silva

2016, Mem Inst Oswaldo Cruz - Article

Natural killer cells require monocytic Gr-1⁺/CD11b⁺ myeloid cells to eradicate orthotopically engrafted glioma cells

P Chockley, GJ Baker, Maria Castro, D Zamler, Pedro Lowenstein

2016, OncoImmunology - Article

Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn on Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model

M Dzaman, N Vanderveen, N Raja, Maria Castro, D Palmer, Pedro Lowenstein, P Ng, Henry Appelman, E Yi, D Zamler

2016, Human Gene Therapy Methods - Article

Fitness, insulin sensitivity, and frontal lobe integrity in adults with overweight and obesity.

Po Yau, Maria Castro, Antonio Convit, Christopher Venutolo

2016, Obesity (Silver Spring) - Article

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