Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
AI Iglesias, A Mishra, V Vitart, Y Bykhovskaya, R Höhn, H Springelkamp, G Cuellar-Partida, P Gharahkhani, JNC Bailey, CE Willoughby, X Li, S Yazar, A Nag, AP Khawaja, O Polašek, D Siscovick, P Mitchell, YC Tham, JL Haines, LS Kearns, C Hayward, Y Shi, EM Van Leeuwen, KD Taylor, JJ Wang, E Rochtchina, J Attia, R Scott, EG Holliday, PN Baird, J Xie, M Inouye, A Viswanathan, X Sim, P Bonnemaijer, JI Rotter, NG Martin, T Zeller, RA Mills, SE Staffieri, JB Jonas, I Schmidtmann, T Boutin, JH Kang, SEM Lucas, TY Wong, ME Beutel, JF Wilson, RR Allingham, MH Brilliant, DL Budenz, WG Christen, J Fingert, DS Friedman, D Gaasterland, T Gaasterland, MA Hauser, P Kraft, RK Lee, Paul Lichter, Y Liu, SJ Loomis, Sayoko Moroi, MA Pericak-Vance, A Realini, JE Richards, JS Schuman, WK Scott, K Singh, AJ Sit, D Vollrath, RN Weinreb, G Wollstein, DJ Zack, K Zhang, P Donnelly, I Barroso, JM Blackwell, E Bramon, MA Brown, JP Casas, A Corvin, P Deloukas, A Duncanson, J Jankowski, HS Markus, CG Mathew, CNA Palmer, R Plomin, A Rautanen, SJ Sawcer, RC Trembath, NW Wood, CCA Spencer, G Band, C Bellenguez, C Freeman, G Hellenthal, E Giannoulatou, M Pirinen
Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma
P Gharahkhani, KP Burdon, JN Cooke Bailey, AW Hewitt, MH Law, LR Pasquale, JH Kang, JL Haines, E Souzeau, T Zhou, OM Siggs, J Landers, M Awadalla, S Sharma, RA Mills, B Ridge, D Lynn, R Casson, SL Graham, I Goldberg, A White, PR Healey, J Grigg, M Lawlor, P Mitchell, J Ruddle, M Coote, M Walland, S Best, A Vincent, J Gale, G Radfordsmith, DC Whiteman, GW Montgomery, NG Martin, DA MacKey, JL Wiggs, S MacGregor, JE Craig, RR Allingham, M Brilliant, DL Budenz, JH Fingert, D Gaasterland, T Gaasterland, L Hark, M Hauser, RP Igo, P Kraft, RK Lee, Paul Lichter, Y Liu, Sayoko Moroi, M Pericak-Vance, A Realini, D Rhee, JE Richards, R Ritch, JS Schuman, WK Scott, K Singh, AJ Sit, D Vollrath, G Wollstein, DJ Zack
Family-based genome-wide association study of south Indian pedigrees supports WNT7B as a central corneal thickness locus
BJ Fan, X Chen, N Sondhi, PF Sharmila, N Soumittra, S Sripriya, S Sacikala, R Asokan, DS Friedman, LR Pasquale, XR Gao, L Vijaya, JC Bailey, V Vitart, S Macgregor, CJ Hammond, CC Khor, JL Haines, R George, JL Wiggs, R Allingham, XR Gao, J Gauderman, M Hauser, JI Rotter, R Varma, J Wiggs, T Aung, KP Burdon, CY Cheng, JE Craig, AJ Cree, P Gharahkhani, AW Hewitt, R Höhn, P Hysi, AI Iglesias Gonzalez, J Jonas, A Khawaja, CC Khor, CCW Klaver, F Pasutto, D Mackey, P Mitchell, A Mishra, C Pang, H Springelkamp, G Thorleifsson, U Thorsteinsdottir, CM van Duijn, A Viswanathan, R Wojciechowski, T Wong, TL Young, T Zeller, M Brilliant, D Budenz, JC Bailey, J Fingert, T Gaasterland, JL Haines, R Igo, JH Kang, P Kraft, R Lee, Paul Lichter, Y Liu, Sayoko Moroi, A Realini, D Rhee, JR Richards, R Ritch, J Schuman, WK Scott, K Singh, A Sit, D Vollrath, RN Weinreb, G Wollstein, D Zack
Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma
R King, FL Struebing, Y Li, J Wang, AA Koch, JN Cooke Bailey, P Gharahkhani, S MacGregor, RR Allingham, MA Hauser, JL Wiggs, EE Geisert, R Allingham, M Brilliant, D Budenz, JC Bailey, J Fingert, T Gaasterland, JL Haines, L Hark, M Hauser, R Igo, JH Kang, P Kraft, R Lee, Paul Lichter, Y Liu, Sayoko Moroi, LR Pasquale, M Pericak-Vance, A Realini, D Rhee, JR Richards, R Ritch, J Schuman, WK Scott, K Singh, A Sit, D Vollrath, RN Weinreb, G Wollstein, D Zack, T Aung, KP Burdon, CY Cheng, JNC Bailey, JE Craig, AJ Cree, CJ Hammond, AW Hewitt, R Höhn, P Hysi, AII Gonzalez, J Jonas, A Khawaja, CC Khor, CCW Klaver, F Pasutto, D Mackey, P Mitchell, A Mishra, C Pang, H Springelkamp, G Thorleifsson, U Thorsteinsdottir, CM van Duijn, A Viswanathan, V Vitart, R Wojciechowski, T Wong, TL Young, T Zeller
Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility
SR Chintalapudi, D Maria, X Di Wang, JNC Bailey, R Allingham, M Brilliant, D Budenz, J Fingert, T Gaasterland, JL Haines, L Hark, M Hauser, R Igo, J Hee Kang, P Kraft, R Lee, Paul Lichter, Y Liu, Sayoko Moroi, LR Pasquale, M Pericak-Vance, A Realini, D Rhee, JR Richards, R Ritch, J Schuman, WK Scott, K Singh, A Sit, D Vollrath, G Wollstein, D Zack, T Aung, P Bonnemaijer, CY Cheng, J Craig, C Van Duijn, P Gharahkhani, A Iglesias Gonzalez, CJ Hammond, A Hewitt, R Hoehn, F Jonansson, A Khawaja, C Chuen Khor, CCW Klaver, A Lotery, D MacKey, S MacGregor, C Pang, F Pasutto, K Stefansson, G Thorleifsson, U Thorsteinsdottir, V Vitart, E Vithana, T Young, T Zeller, PG Hysi, JL Wiggs, RW Williams, MM Jablonski
Assessing the association of mitochondrial genetic variation with primary open-angle glaucoma using gene-set analyses
AP Khawaja, JN Cooke Bailey, JH Kang, R Rand Allingham, MA Hauser, M Brilliant, DL Budenz, WG Christen, J Fingert, D Gaasterland, T Gaasterland, P Kraft, RK Lee, Paul Lichter, Y Liu, F Medeiros, Sayoko Moroi, Julia Richards, T Realini, R Ritch, JS Schuman, WK Scott, K Singh, AJ Sit, D Vollrath, G Wollstein, DJ Zack, K Zhang, M Pericak-Vance, RN Weinreb, JL Haines, LR Pasquale, JL Wiggs
Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium
SS Verma, JN Cooke Bailey, A Lucas, Y Bradford, JG Linneman, MA Hauser, LR Pasquale, PL Peissig, MH Brilliant, CA McCarty, JL Haines, JL Wiggs, TR Vrabec, G Tromp, MD Ritchie, J Bickel, A Chandler, I Holm, I Kohane, S Manzi, K Markianos, N Palmer, C Perry, G Savova, W Wolf, S Wong Kong, A Antommaria, B Cobb, J Harley, J Hutton, T Lingren, J Lynch, K Marsolo, M Myers, B Namjou, C Prows, I Solti, S Vinks, M Wagner, D Abrams, B Almoguera, R Chiavacci, J Connolly, M Devoto, H Hakonarson, B Keating, C Kim, F Mentch, H Qui, P Sleiman, L Tian, L Vazquez, B Bartko, J Bock, K Borthwick, D Carey, R Colonie, R Elston, A Faucett, S Fetterolf, G Gerhard, H Kuivaniemi, D Ledbetter, E Lipsky, S Pendergrass, A Sundaresan, D Smelser, M Williams, C Wood, J Albrecht, C Carlson, D Carrell, P Crane, D Cronkite, D Crosslin, C Davis, K Ehrlich, M Fullterton, C Gallego, A Gordon, J Grafton, K Hansen, A Hartzler, G Jarvik, E Larson, K Leppig, S Mukherjee, J Ralston, A Scrol, P Tarczy-Hornoch, S Trinidad, S Bielinski, K Bruce, C Chute, M De Andrade, H Jouni, J Heit, I Isseh, B Koenig, Paul Lichter, Sayoko Moroi, Julia Richards
A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium
Y Liu, JC Bailey, I Helwa, WM Dismuke, J Cai, M Drewry, MH Brilliant, DL Budenz, WG Christen, DI Chasman, JH Fingert, D Gaasterland, T Gaasterland, MO Gordon, RP Igo, JH Kang, MA Kass, P Kraft, RK Lee, Paul Lichter, Sayoko Moroi, A Realini, Julia Richards, R Ritch, JS Schuman, WK Scott, K Singh, AJ Sit, YE Song, D Vollrath, R Weinreb, F Medeiros, G Wollstein, DJ Zack, K Zhang, MA Pericak-Vance, P Gonzalez, WD Stamer, RW Kuchtey, RR Allingham, MA Hauser, LR Pasquale, JL Haines, JL Wiggs
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
JNC Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, KP Burdon, H Aschard, DI Chasman, RP Igo, PG Hysi, CA Glastonbury, A Ashley-Koch, M Brilliant, AA Brown, DL Budenz, A Buil, CY Cheng, H Choi, WG Christen, G Curhan, I De Vivo, JH Fingert, PJ Foster, C Fuchs, D Gaasterland, T Gaasterland, AW Hewitt, F Hu, DJ Hunter, AP Khawaja, RK Lee, Z Li, Paul Lichter, DA Mackey, P McGuffin, P Mitchell, Sayoko Moroi, SA Perera, KW Pepper, Q Qi, T Realini, Julia Richards, PM Ridker, E Rimm, R Ritch, M Ritchie, JS Schuman, WK Scott, K Singh, AJ Sit, YE Song, RM Tamimi, F Topouzis, AC Viswanathan, SS Verma, D Vollrath, JJ Wang, N Weisschuh, B Wissinger, G Wollstein, TY Wong, BL Yaspan, DJ Zack, K Zhang, RN Weinreb, MA Pericak-Vance, K Small, CJ Hammond, T Aung, Y Liu, EN Vithana, S MacGregor, JE Craig, P Kraft, G Howell, MA Hauser, LR Pasquale, JL Haines, JL Wiggs
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
H Springelkamp, A Mishra, PG Hysi, P Gharahkhani, R Höhn, CC Khor, JN Cooke Bailey, X Luo, WD Ramdas, E Vithana, V Koh, S Yazar, L Xu, H Forward, LS Kearns, N Amin, AI Iglesias, KS Sim, EM van Leeuwen, A Demirkan, S van der Lee, SC Loon, F Rivadeneira, A Nag, PG Sanfilippo, A Schillert, PTVM de Jong, BA Oostra, AG Uitterlinden, A Hofman, T Zhou, KP Burdon, TD Spector, KJ Lackner, SM Saw, JR Vingerling, YY Teo, LR Pasquale, RCW Wolfs, HG Lemij, ES Tai, JB Jonas, CY Cheng, T Aung, NM Jansonius, CCW Klaver, JE Craig, TL Young, JL Haines, S Macgregor, DA Mackey, N Pfeiffer, TY Wong, JL Wiggs, AW Hewitt, CM van Duijn, CJ Hammond, RR Allingham, MH Brilliant, DL Budenz, JNC Bailey, WG Christen, J Fingert, D Gaasterland, T Gaasterland, MA Hauser, JH Kang, P Kraft, RK Lee, PA Lichter, Y Liu, SJ Loomis, Sayoko Moroi, MA Pericak-Vance, A Realini, Julia Richards, JS Schuman, WK Scott, K Singh, AJ Sit, D Vollrath, RN Weinreb, G Wollstein, DJ Zack, K Zhang, Paul Lichter
DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma
Y Liu, ME Garrett, BL Yaspan, JC Bailey, SJ Loomis, M Brilliant, DL Budenz, WG Christen, JH Fingert, D Gaasterland, T Gaasterland, JH Kang, RK Lee, Paul Lichter, Sayoko Moroi, A Realini, Julia Richards, JS Schuman, WK Scott, K Singh, AJ Sit, D Vollrath, R Weinreb, G Wollstein, DJ Zack, K Zhang, MA Pericak-Vance, JL Haines, LR Pasquale, JL Wiggs, RR Allingham, AE Ashley-Koch, MA Hauser
Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma
M Ulmer Carnes, YP Liu, RR Allingham, BT Whigham, S Havens, ME Garrett, C Qiao, N Katsanis, JL Wiggs, LR Pasquale, A Ashley-Koch, EC Oh, MA Hauser, M Brilliant, DL Budenz, HR Chin, J Cooke Bailey, J Fingert, DS Friedman, D Gaasterland, T Gaasterland, J Haines, MA Hauser, JH Kang, RK Lee, Paul Lichter, Y Liu, S Loomis, CE McCarty, Sayoko Moroi, M Pericak-Vance, A Realini, Julia Richards, JS Schuman, WK Scott, K Singh, A Sit, D Vollrath, RN Weinreb, G Wollstein, BL Yaspan, D Zack, K Zhang
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