Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans
M Flickinger, AE Locke, RM Myers, Melvin McInnis, S Zöllner, JB Vincent, M McGue, SJ Watson, JL Sobell, HM Kang, M Zawistowski, Q Lu, WG Iacono, S Levy, M Rivera, Margit Burmeister, JA Knowles, Laura Scott, Stanley Watson Jr, D Absher, L Legrand, J Carlson, S Cohen-Woods, Sebastian Zoellner, G Breen, Michael Boehnke, Jun Li, Huda Akil, MT Pato
Rare loss of function variants in candidate genes and risk of colorectal cancer
CH Newton-Cheh, M Barbalic, NO Stitziel, P Concannon, T Fennell, D Goff, RG Barr, N Stoletzki, V Funari, M Horike-Pyne, KT Vickers, JA Spertus, AL DeStefano, E Akylbekova, J Crosby, J Carr, Cristen Willer, SS Rich, J Gardin, WM Grady, SB Gabriel, R Do, EA Rosenthal, M Budoff, S Cresci, Y Hu, DN Farlow, LM Amendola, H Allayee, R Nassir, E Fox, K Garimella, M Fornage, G Burke, LA Cupples, M Li, W Grody, A Kiezun, DM Jordan, D Reich, HM Kang, RL Bennett, PIW de Bakker, MO Dorschner, BH Shirts, U Peters, S Buxbaum, C Li, MA DePristo, DM Altshuler, S Padmanabhan, DS Siscovick, FM Hisama, JP Durda, E Boerwinkle, O Gordon, P Donnelly, PD Robertson, AR Folsom, MA Rivas, DW Bowden, LD Atwood, Jeffrey Kidd, MP Reilly, R D’Agostino, MJ Daly, Santhi Ganesh, EJ Benjamin, SL Hazen, BF Voight, DA Nickerson, GR Abecasis, J Bis, S Pulit, Laura Scott, DJ Rader, GP Jarvik, G Lettre, J Dupuis, J Brody, S Kathiresan, A Dreisbach, IB Stanaway, CM Ballantyne, WM Chen, G Peloso, J Ellis, G Jun, SR Sunyaev, S Schwartz
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
Laura Scott, V Haroutunian, V Escott-Price, P Lee, P Giusti-Rodriguez, JD Favero, Michael Boehnke, Fan Meng, A Corvin, Melvin McInnis, L de Haan, KL Davis, B Crespo-Facorro, Sebastian Zoellner, SA Bacanu, BK Andreassen, Margit Burmeister, M Albus, MJ Cairns, M Davidson, JTR Walters, RCK Chan, Stanley Watson Jr, N Durmishi, V Zuber, TH Pers, S Gopal, SV Catts, WK Thompson, DW Black, D Campion, NG Buccola, I Giegling, V Golimbet, L Essioux, VJ Carr, JJ Crowley, B Bulik-Sullivan, S Godard, MS Farrell, F Degenhardt, RM Cantor, F Dudbridge, G Donohoe, E Drapeau, W Cahn, NB Freimer, JI Friedman, T Hansen, J Bene, AH Fanous, M Alexander, AM Hartmann, ES Gershon, ML Hamshere, P Eichhammer, EFC Cheung, A Frigessi, H Huang, FA Henskens, C Hammer, P Cormican, S Herms, CR Cloninger, M LeBlanc, F Amin, N Carrera, T Dinan, E Bevilacqua, KD Chambert, J Duan, L Georgieva, Robert Thompson, RA Belliveau, J Frank, E Agerbo, I Agartz, M Friedl, JI Goldstein, D Dikeos, N Cohen, SA Chong, R Freedman, LE DeLisi, L Franke, R Bruggeman, S Ripke, TB Bigdeli, BM Neale, EYH Chen, M Begemann, W Cheng, J Eriksson, D Demontis, KH Farh, J Gratten, G Genovese, G Cai, OA Andreassen, N Craddock, RL Buckner, DA Collier, D Curtis, M Fromer
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
EA Stahl, MJ Cairns, CR Cloninger, F Amin, B Bulik-Sullivan, TB Bigdeli, AD Borglum, R Bruggeman, JM Biernacka, Margit Burmeister, SA Bacanu, SV Catts, JD Buxbaum, SJ Bumpstead, N Carrera, W Cheng, LMO Loohuis, DA Collier, RCK Chan, JMW Pavlides, R Adolfsson, DHR Blackwood, AW Charney, M Albus, W Coryell, A McQuillin, TD Als, M Baekvad-Hansen, VJ Carr, M Alexander, JA Badner, M Alda, E Agerbo, S Papiol, Huda Akil, RM Cantor, Robert Thompson, SE Bergen, M Boks, RYL Chen, I Agartz, Laura Scott, S Bender, W Bunney, M Budde, P Cervantes, Stanley Watson Jr, EFC Cheung, N Craddock, N Cohen, C Bellenguez, M Bauer, H Blackburn, TK Clarke, SA Chong, A Anjorin, G Cai, N Bass, Michael Boehnke, DW Craig, V Trubetskoy, JL Kalman, BT Baune, N Mullins, J Bybjerg-Grauholm, RA Belliveau, Melvin McInnis, G Band, I Barroso, S Awasthi, DM Ruderfer, DW Black, KD Chambert, W Cahn, JRI Coleman, RL Buckner, D Albani, S Ripke, W Byerley, J Boocock, N Alliey-Rodriguez, WH Berrettini, NG Buccola, MJ Arranz, S Bakker, Fan Meng, E Bramon, JD Barchas, APS Ori, M Begemann, JM Blackwell, D Campion, J Bene, F Bellivier, Sebastian Zoellner, G Breen, MA Brown, E Bevilacqua, M Casas, A Di Florio, P Cormican, CB Pedersen, E Domenici
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
AE Locke, AG Day-Williams, V Agarwala, KJ Gaulton, HM Lee, JF Tajes, MK Ikram, V Giedraitis, MCY Ng, D Prabhakaran, RP Welch, Michael Boehnke, JMM Howson, A Mahajan, JR Huyghe, KH Lin, HM Stringham, B Balkau, MS Kwon, CP Jenkinson, Y Lu, Laura Scott, N Grarup, J Huang, DJ McCarthy, N Barzilai, TJ Maxwell, J Scott, C Hu, L Caulkins, S Purcell, Y Nagai, MJ Go, BG Han, D Pasko, SCJ Parker, P Kwan, JE Below, TM Teslovich, VKL Lam, JRB Perry, PS Chines, J Danesh, TV Varga, T Ferreira, J Kuusisto, M Müller-Nurasyid, RD Pearson, HM Highland, C Fuchsberger, T Kuulasmaa, ML Stitzel, I Huh, P Cingolani, H Boeing, A Stančáková, G Grant, M Horikoshi, ER Gamazon, L Moutsianas, NW Rayner, C Hartl, TW Blackwell, T Fingerlin, ND Palmer, J Yoon, A Kumar, SH Kwak, M van de Bunt, CM Lindgren, KS Park, AS Butterworth, W Zhang, J Carey, MA Rivas, R Koesterer, C Ma, Goncalo Abecasis, T Green, P Chen, J Flannick, NR Robertson, W Zhao, BF Voight, O Gottesman, X Wang, A Manning, AU Jackson, J Dupuis, HE Abboud, X Sim, BM Neale, JD Smith, NL Beer, YJ Kim
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
C Ma, TJ Maxwell, M Van De Bunt, AG Day-Williams, X Wang, J Huang, V Agarwala, C Hartl, AE Locke, J Flannick, TW Blackwell, W Zhang, T Ferreira, M Müller-Nurasyid, PS Chines, S Lee, T Green, NR Robertson, JF Tajes, J Dupuis, Michael Boehnke, D Pasko, A Mahajan, MA Rivas, NL Beer, KJ Gaulton, HM Stringham, P Cingolani, CM Lindgren, X Sim, J Kuusisto, T Kuulasmaa, HM Highland, JE Below, Stephen Parker, H Chen, N Grarup, L Moutsianas, T Fingerlin, DJ McCarthy, Y Kim, I Huh, M Horikoshi, RD Pearson, Hyun Kang, RA Scott, J Yoon, RP Welch, JR Huyghe, AU Jackson, Y Nagai, MK Ikram, R Koesterer, C Fuchsberger, TM Teslovich, JRB Perry, A Kumar, NW Rayner, J Lee, YJ Kim, ML Stitzel, MJ Go, ER Gamazon, L Caulkins, CP Jenkinson, Laura Scott, MS Kwon, P Chen, BG Han, C Hu, Goncalo Abecasis, KH Lin, BF Voight, TV Varga, N Barzilai, Y Chen
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
H Campbell, JA Cauley, K Estrada, LM Yerges-Armstrong, M Erdos, J Hua Zhao, L Byberg, L Stolk, IB Borecki, Laura Scott, G Thorleifsson, M Bochud, RAM Dhonukshe-Rutten, J Eriksson, L Broer, I Barroso, G Eiriksdottir, Z Chen, PL De Jager, DS Evans, MC Zillikens, F Collins, Michael Boehnke, NL Glazer, R Biffar, N Campos Obanda, L Vandenput, I Demuth, Stephen Parker, AS Buchman, I Malkin, YH Hsu, AW Enneman, DL Koller, PM Cawthon, L Bertram, T Johnson, M Claussnitzer, M Garcia, M Fu, K Åkesson, WC Chou, NH Cho, T Girke, C Gieger, A Aghdassi, J Luan, MF Feitosa, JG Eriksson, N Amin, H Jin Choi, H Cederberg, AV Smith, S Demissie, G Livshits, JS Ried, L DIatchenko, H Grallert, W Zhang, Z Kutalik, SR Cummings, LJ Baier, DA Bennett
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis
Michael Boehnke, S Walitza, CJ Scholz, N Williams, B Franke, A Hervas, RJL Anney, F Mulas, M Ribasés, MC O’Donovan, KP Lesch, RD Oades, BM Neale, K Langley, AE Doyle, HC Steinhausen, TJ Banaschewski, OA Andreassen, A Anjorin, EJS Sonuga-Barke, A Todorov, MJ Arranz, A Arias-Vasquez, TB Barrett, MJ Daly, Sebastian Zoellner, A Miranda, A Thapar, J Biederman, N Bass, S Dalsgaard, AA Vasquez, SV Faraone, JA Ramos-Quiroga, KJE van Hulzen, JK Buitelaar, L Backlund, EJ Sonuga-Barke, F Bellivier, M Gill, C Sánchez-Mora, J Martin, Laura Scott, L Kent, R Schachar, SV Faraone, H Roeyers, J Crosbie, A Warnke, D Absher, M Romanos, H Weber, J Meyer, SF Nelson, Melvin McInnis, S Ripke, J Sergeant, P Asherson, MJ Owen, A Charach, Margit Burmeister, M Landén, Y Wang, SE Medland, Robert Thompson, JD Barchas, A McQuillin, H Akil, M Bauer, SL Smalley, J Kuntsi, E Mick, M Casas, B Franke, N Lambregts-Rommelse, JJ McGough, JR Kelsoe, SK Loo, P Holmans, Stanley Watson Jr, B Cormand, Y Zhang-James, S Ripke, A Rothenberger, H Palmason, C Freitag, M Klein, A Reif, J Elia, JA Badner, RP Ebstein, H Hakonarson, M Bayés
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
C Ma, M Kaakinen, A Mahajan, P Almgren, Laura Scott, Y Lu, AU Jackson, NW Rayner, BF Voight, M Li, JD Eicher, L Liang, D Thuillier, G Thorleifsson, P Kwan, SM Willems, NR Van Zuydam, CT Liu, HA Kestler, R Benediktsson, J Luan, LC Karssen, V Steinthorsdottir, H Chen, RJ Strawbridge, E Mihailov, M Frånberg, N Robertson, P Chanda, T Meitinger, JS Ried, TM Teslovich, N Pervjakova, R Mägi, H Grallert, L Marullo, T Esko, Y Lee, Michael Boehnke, A Kong, Goncalo Abecasis, AD Johnson, L Eisele, AB Hreidarsson, G Sigurðsson, T Sparso, L Yengo, H Chheda, L Jiang, M Müller-Nurasyid, EM van Leeuwen, TH Pers, T Ferreira, S Gustafsson, KJ Gaulton, RA Scott, B Thorand, D Rybin, M Roden, ND Kerrison, B Isomaa, C Fox, L Qi, C Fuchsberger, C Dina
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa
R Burghardt, A Hinney, L Carlberg, O Andreassen, G Breen, R Walters, J Barrett, V Bencko, M Daly, H Gaspar, S Ripke, E Zeggini, CM Bulik, J Goldstein, T Ando, B Bulik-Sullivan, Laura Scott, VB Perica, H Aschauer, PF Sullivan, Z Yilmaz, M Cassina, A Birgegård, J Goldstein, L Thornton, Roger Cone, L Alfredsson, V Anttila, R Walters, C Boni, R Adan, W Berrettini, H Gaspar, J Baker, L Duncan, H Brandt, A Bergen
Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease
JF Peden, D Tregouet, A Hamsten, LC Becker, Patricia Peyser, A Goel, A Silveira, BO Boehm, Laura Scott, M Karakas, JC Bis, Jennifer Bragg-Gresham, B Sennblad, N Klopp, F Cambien, Alan Weder, PJ Grant, JH Moore, JB Meigs, Q Yang, RJ Strawbridge, JC Chambers, BM Psaty, JD Eicher, TD Spector, Sharon Kardia, J Öhrvik, JS Kooner, C Song, W Koenig, KM Rice, TB Harris, V Truong, B McKnight, Santhi Ganesh, J Ding, S Burgess, DI Chasman, AV Smith, M Sabater-Lleal, AG Uitterlinden, MG Franzosi, K Taylor, J Huang, W März, AC Syvänen, JC Mychaleckyj, PE Morange, CJ O'Donnell, M Müller-Nurasyid, EMC Schrijvers, G Silbernagel, M Bochud, S Kathiresan, BR Winkelmann, WH van Gilst, T Oudot-Mellakh, R Clarke, J Danesh, Y Liu, MA Ikram, LR Yanek, GH Tofler, N Soranzo, Lawrence Bielak, N Matijevic, W Tang, M Cushman, HL Hillege, A Peters, P Eriksson, A Dehghan, ME Kleber, FMK Williams, U Seedorf, K Lohman, H Watkins, FW Asselbergs, AH Goodall, MH Chen, JC Hopewell, Michael Boehnke, Goncalo Abecasis, SY Shin, AD Johnson, D Saleheen, MP Reilly, P van der Harst, RP Tracy, A Franco-Cereceda, PB Munroe, C Meisinger, L Folkersen, J Baumert, R Collins, AM Carter, P Lundmark, GB Ehret, S Basu, GJ Navis, AR Folsom
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits
AJ Lusis, A He, J Kuusisto, PS Gargalovic, KL Mohlke, C Pan, AU Jackson, BW Parks, C Tilford, CK Raulerson, M Civelek, Y Wu, A Stančáková, P Pajukanta, Michael Boehnke, A Ko, M Laakso, HM Stringham, NK Saleem, C Fuchsberger, PS Chines, Laura Scott, T Kirchgessner, KS Small, N Narisu, FS Collins
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
R Watanabe, BN Wolford, R Kursawe, MR Erdos, S Vadlamudi, A Kirilusha, KL Mohlke, N Narisu, Michael Boehnke, ML Stitzel, ME Cannon, DL Taylor, LL Bonnycastle, RDO Albanus, PS Chines, P Orchard, RP Welch, JP Didion, Laura Scott, A Varshney, FS Collins, Stephen Parker, J Hensley
Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees
R Sladek, M DePristo, X Liu, AP Morris, J Dupuis, J Laramie, KJ Gaulton, T Dyer, J Grundstad, J Maller, S Zöllner, AL Williams, P Cingolani, T Park, G Jun, J Lee, M Zawistowski, TW Blackwell, JG Wilson, P Fontanillas, RG Tearle, Sebastian Zoellner, PS Chines, R King, C Fuchsberger, YJ Kim, TM Teslovich, TI Pollin, JC Florez, YY Teo, Laura Scott, B Akolkar, G Atzmon, O Livne, S Choi, M Almeida, JE Below, V Trubetskoy, T Fingerlin, D Lehman, GI Bell, Michael Boehnke, Goncalo Abecasis, J Peralta, KL Mohlke, NJ Cox, CL Hanis, A Heath, NP Burtt, H Chen, C Churchhouse, MA Rivas, S Feng, DL Nicolae, JE Curran, M Seielstad, A Manning, C McKeon, AE Locke, AR Wood, A Mazur, D Reich, S Won, D Ragona, SE Lincoln, H Li, X Sim, R Grossman
A reference panel of 64,976 haplotypes for genotype imputation
H Campbell, C Sidore, Y Luo, K Sharp, FS Collins, JC Barrett, A Angius, U Peters, RM Fraser, S Levy, H Zhang, D Melzer, C Fuchsberger, AE Farmaki, W Kretzschmar, P Danecek, M Dorr, E Chew, Michael Boehnke, S Gabriel, Laura Scott, D Boomsma, A Kwong, S McCarthy, M Mezzavilla, CM Van Duijn, KL Mohlke, Matthew Sampson, JL Min, Hyun Kang, Chad Brummett, Melvin McInnis, M Pato, Goncalo Abecasis, O Delaneau, GD Smith, M McGue, L Ferrucci, F Busonero, S Chen, JC Lee, Matthias Kretzler, L Groop, CE Gillies, A Chan, A Palotie, A Gilly, A Teumer, AR Wood, S Vrieze, T Harrison, OL Holmen, S Das, M Cocca, JB Vincent, LJ Corbin, Kari Branham, Cristen Willer, L Forer, A Hattersley, I Gandin, N Pirastu, A Mahajan, S Koskinen, M Nauck, J Veldink, G Dedoussis, G Breen, M Traglia, D Nickerson, K Hveem, T Meitinger, N Timpson
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