Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
JB Nielsen, Lars Fritsche, W Zhou, TM Teslovich, OL Holmen, S Gustafsson, ME Gabrielsen, EM Schmidt, R Beaumont, BN Wolford, M Lin, Chad Brummett, MH Preuss, L Refsgaard, EP Bottinger, SE Graham, I Surakka, Y Chu, AH Skogholt, H Dalen, Alan Boyle, Hakan Oral, Todd Herron, Jacob Kitzman, Jose Jalife, JH Svendsen, MS Olesen, I Njølstad, ML Løchen, A Baras, O Gottesman, A Marcketta, C O'Dushlaine, MD Ritchie, T Wilsgaard, RJF Loos, TM Frayling, Michael Boehnke, E Ingelsson, DJ Carey, FE Dewey, Hyun Kang, Goncalo Abecasis, K Hveem, Cristen Willer
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
J Flannick, C Fuchsberger, A Mahajan, TM Teslovich, V Agarwala, KJ Gaulton, L Caulkins, R Koesterer, C Ma, L Moutsianas, DJ McCarthy, MA Rivas, JRB Perry, X Sim, TW Blackwell, NR Robertson, NW Rayner, P Cingolani, AE Locke, JF Tajes, HM Highland, J Dupuis, PS Chines, CM Lindgren, C Hartl, AU Jackson, H Chen, JR Huyghe, M Van De Bunt, RD Pearson, A Kumar, M Müller-Nurasyid, N Grarup, HM Stringham, ER Gamazon, S Lee, Y Chen, RA Scott, JE Below, P Chen, J Huang, MJ Go, ML Stitzel, D Pasko, Stephen Parker, TV Varga, T Green, NL Beer, AG Day-Williams, T Ferreira, T Fingerlin, M Horikoshi, C Hu, I Huh, MK Ikram, YJ Kim, Y Kim, MS Kwon, J Lee, KH Lin, TJ Maxwell, Y Nagai, X Wang, RP Welch, J Yoon, W Zhang, N Barzilai, BF Voight, BG Han, CP Jenkinson, T Kuulasmaa, J Kuusisto, A Manning, MCY Ng, ND Palmer, B Balkau, A Stančáková, HE Abboud, H Boeing, V Giedraitis, D Prabhakaran, O Gottesman, J Scott, J Carey, P Kwan, G Grant, JD Smith, BM Neale, S Purcell, AS Butterworth, JMM Howson, HM Lee, Y Lu, SH Kwak, W Zhao, J Danesh, VKL Lam, KS Park, Hyun Kang, Goncalo Abecasis, Michael Boehnke
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data
SA Bien, PL Auer, TA Harrison, C Qu, CM Connolly, PG Greenside, S Chen, SI Berndt, S Bézieau, Hyun Kang, J Huyghe, H Brenner, G Casey, AT Chan, JL Hopper, BL Banbury, J Chang-Claude, SJ Chanock, RW Haile, M Hoffmeister, C Fuchsberger, MA Jenkins, SM Leal, M Lemire, PA Newcomb, S Gallinger, JD Potter, RE Schoen, ML Slattery, JD Smith, L Le Marchand, E White, BW Zanke, GR Abeçasis, CS Carlson, U Peters, DA Nickerson, A Kundaje, L Hsu, Goncalo Abecasis
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk
I Brænne, L Zeng, C Willenborg, V Tragante, T Kessler, Cristen Willer, M Laakso, L Wallentin, PW Franks, V Salomaa, A Dehghan, T Meitinger, NJ Samani, FW Asselbergs, J Erdmann, H Schunkert, P Deloukas, S Kanoni, M Farrall, TL Assimes, JR Thompson, E Ingelsson, D Saleheen, BA Goldstein, D Absher, IR König, K Stirrups, Å Johansson, AS Hall, JY Lee, JC Chambers, T Esko, L Folkersen, A Goel, E Grundberg, AS Havulinna, WK Ho, JC Hopewell, N Eriksson, ME Kleber, K Kristiansson, A Lundmark, LP Lyytikäinen, S Rafelt, D Shun, RJ Strawbridge, G Thorleifsson, E Tikkanen, N Van Zuydam, BF Voight, LL Waite, W Zhang, A Zieg, D Altshuler, AJ Balmforth, I Barroso, PS Braund, C Burgdorf, S Claudi-Boehm, D Cox, M Dimitriou, R Do, ASF Doney, NE El Mokhtari, P Eriksson, K Fischer, P Fontanillas, A Franco-Cereceda, B Gigante, L Groop, S Gustafsson, J Hager, G Hallmans, BG Han, S Ehunt, Hyun Kang, T Illig, JW Knowles, G Kolovou, J Kuusisto, C Langenberg, C Langford, K Leander, ML Lokki, MI McCarthy, C Meisinger, O Melander, E Mihailov, S Maouche, AD Morris, M Müller-Nurasyid, K Nikus, JF Peden, NW Rayner, A Rasheed, S Rosinger, D Rubin, MP Rumpf, A Schäfer, Michael Boehnke
Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
Bo Yang, W Zhou, J Jiao, JB Nielsen, Michael Mathis, M Heydarpour, G Lettre, L Folkersen, S Prakash, C Schurmann, Lars Fritsche, GA Farnum, M Lin, M Othman, W Hornsby, A Driscoll, A Levasseur, M Thomas, L Farhat, MP Dubé, EM Isselbacher, A Franco-Cereceda, DC Guo, EP Bottinger, G Deeb, A Booher, Sachin Kheterpal, Yuqing Chen, Hyun Kang, Jacob Kitzman, HJ Cordell, BD Keavney, JA Goodship, Santhi Ganesh, Goncalo Abecasis, Kim Eagle, Alan Boyle, RJF Loos, P Eriksson, JC Tardif, Chad Brummett, DM Milewicz, SC Body, Cristen Willer, Yanbo Fan, Lin Chang
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
Lam Tsoi, PE Stuart, C Tian, Johann Gudjonsson, S Das, M Zawistowski, E Ellinghaus, JN Barker, V Chandran, N Dand, KC Duffin, C Enerbäck, T Esko, A Franke, DD Gladman, P Hoffmann, K Kingo, S Kõks, GG Krueger, HW Lim, A Metspalu, U Mrowietz, S Mucha, P Rahman, A Reis, Trilokraj Tejasvi, R Trembath, John Voorhees, S Weidinger, M Weichenthal, Xiaoquan Wen, N Eriksson, Hyun Kang, DA Hinds, Rajan Nair, Goncalo Abecasis, James Elder
A reference panel of 64,976 haplotypes for genotype imputation
S McCarthy, S Das, W Kretzschmar, O Delaneau, AR Wood, A Teumer, Hyun Kang, C Fuchsberger, P Danecek, K Sharp, Y Luo, C Sidore, A Kwong, N Timpson, S Koskinen, S Vrieze, LJ Scott, H Zhang, A Mahajan, J Veldink, U Peters, M Pato, CM Van Duijn, CE Gillies, I Gandin, M Mezzavilla, A Gilly, M Cocca, M Traglia, A Angius, JC Barrett, D Boomsma, Kari Branham, G Breen, Chad Brummett, F Busonero, H Campbell, A Chan, S Chen, E Chew, FS Collins, LJ Corbin, GD Smith, G Dedoussis, M Dorr, AE Farmaki, L Ferrucci, L Forer, RM Fraser, S Gabriel, S Levy, L Groop, T Harrison, A Hattersley, OL Holmen, K Hveem, Matthias Kretzler, JC Lee, M McGue, T Meitinger, D Melzer, JL Min, KL Mohlke, JB Vincent, M Nauck, D Nickerson, A Palotie, N Pirastu, Melvin McInnis, JB Richards, C Sala, V Salomaa, D Schlessinger, S Schoenherr, PE Slagboom, K Small, T Spector, D Stambolian, M Tuke, J Tuomilehto, LH Van Den Berg, W Van Rheenen, U Volker, C Wijmenga, D Toniolo, E Zeggini, P Gasparini, Matthew Sampson, JF Wilson, T Frayling, PIW De Bakker, MA Swertz, S McCarroll, C Kooperberg, A Dekker, D Altshuler, Cristen Willer, W Iacono, S Ripatti, Michael Boehnke, Goncalo Abecasis
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
GB Ehret, T Ferreira, DI Chasman, AU Jackson, EM Schmidt, T Johnson, G Thorleifsson, J Luan, LA Donnelly, S Kanoni, AK Petersen, V Pihur, RJ Strawbridge, D Shungin, MF Hughes, O Meirelles, M Kaakinen, N Bouatia-Naji, K Kristiansson, S Shah, ME Kleber, X Guo, LP Lyytikäinen, C Fava, N Eriksson, IM Nolte, PK Magnusson, EL Salfati, LS Rallidis, E Theusch, AJP Smith, L Folkersen, K Witkowska, TH Pers, R Joehanes, SK Kim, L Lataniotis, R Jansen, AD Johnson, H Warren, YJ Kim, W Zhao, Y Wu, BO Tayo, M Bochud, D Absher, LS Adair, N Amin, DE Arking, T Axelsson, D Baldassarre, B Balkau, S Bandinelli, MR Barnes, I Barroso, S Bevan, JC Bis, G Bjornsdottir, Michael Boehnke, E Boerwinkle, LL Bonnycastle, DI Boomsma, SR Bornstein, MJ Brown, M Burnier, CP Cabrera, JC Chambers, IS Chang, CY Cheng, PS Chines, RH Chung, FS Collins, JM Connell, A Döring, J Dallongeville, J Danesh, U De Faire, G Delgado, AF Dominiczak, ASF Doney, F Drenos, S Edkins, JD Eicher, R Elosua, S Enroth, J Erdmann, P Eriksson, T Esko, E Evangelou, A Evans, T Fall, M Farrall, JF Felix, J Ferrières, L Ferrucci, M Fornage, T Forrester, N Franceschini, OH Franco, A Franco-Cereceda, Cristen Willer, Santhi Ganesh, Hyun Kang, Alan Weder
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, KJ Gaulton, C Ma, P Fontanillas, L Moutsianas, DJ McCarthy, MA Rivas, JRB Perry, X Sim, TW Blackwell, NR Robertson, NW Rayner, P Cingolani, AE Locke, JF Tajes, HM Highland, J Dupuis, PS Chines, CM Lindgren, C Hartl, AU Jackson, H Chen, JR Huyghe, M Van De Bunt, RD Pearson, A Kumar, M Müller-Nurasyid, N Grarup, HM Stringham, ER Gamazon, S Lee, Y Chen, RA Scott, JE Below, P Chen, J Huang, MJ Go, ML Stitzel, D Pasko, Stephen Parker, TV Varga, T Green, NL Beer, AG Day-Williams, T Ferreira, T Fingerlin, M Horikoshi, C Hu, I Huh, MK Ikram, YJ Kim, Y Kim, MS Kwon, J Lee, KH Lin, TJ Maxwell, Y Nagai, X Wang, RP Welch, J Yoon, W Zhang, N Barzilai, BF Voight, BG Han, CP Jenkinson, T Kuulasmaa, J Kuusisto, A Manning, MCY Ng, ND Palmer, B Balkau, A Stančáková, HE Abboud, H Boeing, V Giedraitis, D Prabhakaran, O Gottesman, J Scott, J Carey, P Kwan, G Grant, JD Smith, BM Neale, S Purcell, AS Butterworth, JMM Howson, HM Lee, Y Lu, SH Kwak, W Zhao, J Danesh, VKL Lam, KS Park, D Saleheen, Hyun Kang, Michael Boehnke, Goncalo Abecasis
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture
PE Stuart, Rajan Nair, Lam Tsoi, Trilokraj Tejasvi, S Das, Hyun Kang, E Ellinghaus, V Chandran, K Callis-Duffin, Robert Ike, Yanming Li, Xiaoquan Wen, C Enerbäck, Johann Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, John Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, Goncalo Abecasis, James Elder, Yi Li
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, A Mahajan, A Locke, NW Rayner, N Robertson, RA Scott, I Prokopenko, LJ Scott, T Green, T Sparso, D Thuillier, L Yengo, H Grallert, S Wahl, M Frånberg, RJ Strawbridge, H Kestler, H Chheda, L Eisele, S Gustafsson, V Steinthorsdottir, G Thorleifsson, L Qi, LC Karssen, EM Van Leeuwen, SM Willems, M Li, H Chen, C Fuchsberger, P Kwan, C Ma, M Linderman, Y Lu, SK Thomsen, JK Rundle, NL Beer, M Van De Bunt, A Chalisey, Hyun Kang, BF Voight, Goncalo Abecasis, P Almgren, D Baldassarre, B Balkau, R Benediktsson, M Blüher, H Boeing, LL Bonnycastle, EP Bottinger, NP Burtt, J Carey, G Charpentier, PS Chines, MC Cornelis, DJ Couper, AT Crenshaw, RM Van Dam, ASF Doney, M Dorkhan, S Edkins, JG Eriksson, T Esko, E Eury, J Fadista, J Flannick, P Fontanillas, C Fox, PW Franks, K Gertow, C Gieger, B Gigante, O Gottesman, GB Grant, N Grarup, CJ Groves, M Hassinen, CT Have, C Herder, OL Holmen, AB Hreidarsson, SE Humphries, DJ Hunter, AU Jackson, A Jonsson, ME Jørgensen, T Jørgensen, WHL Kao, ND Kerrison, L Kinnunen, N Klopp, A Kong, P Kovacs, P Kraft, J Kravic, C Langford, Michael Boehnke
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
C Sidore, F Busonero, A Maschio, E Porcu, S Naitza, M Zoledziewska, A Mulas, G Pistis, M Steri, F Danjou, A Kwong, VDO Del Vecchyo, CWK Chiang, Jennifer Bragg-Gresham, M Pitzalis, R Nagaraja, B Tarrier, C Brennan, S Uzzau, C Fuchsberger, R Atzeni, F Reinier, R Berutti, J Huang, NJ Timpson, D Toniolo, P Gasparini, G Malerba, G Dedoussis, E Zeggini, N Soranzo, C Jones, R Lyons, A Angius, Hyun Kang, J Novembre, S Sanna, D Schlessinger, F Cucca, Goncalo Abecasis
A global reference for human genetic variation
A Auton, Goncalo Abecasis, DM Altshuler, RM Durbin, DR Bentley, A Chakravarti, AG Clark, P Donnelly, EE Eichler, P Flicek, SB Gabriel, RA Gibbs, ED Green, ME Hurles, BM Knoppers, JO Korbel, ES Lander, C Lee, H Lehrach, ER Mardis, GT Marth, GA McVean, DA Nickerson, JP Schmidt, ST Sherry, G Wang, RK Wilson, E Boerwinkle, H Doddapaneni, Y Han, V Korchina, C Kovar, S Lee, D Muzny, JG Reid, Y Zhu, Y Chang, Q Feng, X Fang, X Guo, M Jian, H Jiang, X Jin, T Lan, Y Li, X Liu, Y Lu, X Ma, M Tang, R Wu, X Xu, Y Yin, W Zhang, M Zhao, X Zheng, N Gupta, N Gharani, LH Toji, NP Gerry, AM Resch, J Barker, L Clarke, L Gil, SE Hunt, G Kelman, E Kulesha, R Leinonen, WM McLaren, R Radhakrishnan, A Roa, D Smirnov, RE Smith, I Streeter, A Thormann, I Toneva, B Vaughan, X Zheng-Bradley, R Grocock, S Humphray, T James, Z Kingsbury, R Sudbrak, MW Albrecht, VS Amstislavskiy, TA Borodina, M Lienhard, F Mertes, M Sultan, B Timmermann, ML Yaspo, L Fulton, V Ananiev, Hyun Kang, Ryan Mills, Jeffrey Kidd, Lars Fritsche
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