Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
Cristen Willer, L Refsgaard, M Lin, MH Preuss, FE Dewey, SE Graham, A Baras, I Njølstad, Todd Herron, AH Skogholt, RJF Loos, Lars Fritsche, H Dalen, MS Olesen, R Beaumont, Goncalo Abecasis, Jose Jalife, Chad Brummett, JH Svendsen, EP Bottinger, Jacob Kitzman, I Surakka, BN Wolford, A Marcketta, TM Teslovich, S Gustafsson, T Wilsgaard, OL Holmen, ME Gabrielsen, Y Chu, JB Nielsen, O Gottesman, DJ Carey, W Zhou, ML Løchen, Hakan Oral, E Ingelsson, C O'Dushlaine, Alan Boyle, K Hveem, Michael Boehnke, MD Ritchie, Hyun Kang, EM Schmidt, TM Frayling
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
C Ma, TJ Maxwell, M Van De Bunt, AG Day-Williams, X Wang, J Huang, V Agarwala, C Hartl, AE Locke, J Flannick, TW Blackwell, W Zhang, T Ferreira, M Müller-Nurasyid, PS Chines, S Lee, T Green, NR Robertson, JF Tajes, J Dupuis, Michael Boehnke, D Pasko, A Mahajan, MA Rivas, NL Beer, KJ Gaulton, HM Stringham, P Cingolani, CM Lindgren, X Sim, J Kuusisto, T Kuulasmaa, HM Highland, JE Below, Stephen Parker, H Chen, N Grarup, L Moutsianas, T Fingerlin, DJ McCarthy, Y Kim, I Huh, M Horikoshi, RD Pearson, Hyun Kang, RA Scott, J Yoon, RP Welch, JR Huyghe, AU Jackson, Y Nagai, MK Ikram, R Koesterer, C Fuchsberger, TM Teslovich, JRB Perry, A Kumar, NW Rayner, J Lee, YJ Kim, ML Stitzel, MJ Go, ER Gamazon, L Caulkins, CP Jenkinson, Laura Scott, MS Kwon, P Chen, BG Han, C Hu, Goncalo Abecasis, KH Lin, BF Voight, TV Varga, N Barzilai, Y Chen
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data
JD Smith, SJ Chanock, E White, U Peters, TA Harrison, BL Banbury, CM Connolly, J Chang-Claude, CS Carlson, PL Auer, ML Slattery, SM Leal, L Le Marchand, L Hsu, J Huyghe, H Brenner, RW Haile, JL Hopper, AT Chan, C Fuchsberger, M Lemire, BW Zanke, GR Abeçasis, RE Schoen, MA Jenkins, S Bézieau, A Kundaje, C Qu, Goncalo Abecasis, S Gallinger, M Hoffmeister, Hyun Kang, SI Berndt, SA Bien, JD Potter, DA Nickerson, PA Newcomb, PG Greenside, S Chen, G Casey
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk
Michael Boehnke, AS Hall, V Tragante, Cristen Willer, J Erdmann, L Wallentin, A Goel, L Zeng, IR König, BA Goldstein, PW Franks, AS Havulinna, I Brænne, H Schunkert, ME Kleber, T Kessler, D Saleheen, M Farrall, JC Hopewell, E Ingelsson, LP Lyytikäinen, K Kristiansson, JC Chambers, Å Johansson, TL Assimes, E Grundberg, D Shun, NJ Samani, N Eriksson, JY Lee, M Laakso, P Lundmark, P Deloukas, Hyun Kang, WK Ho, V Salomaa, T Esko, FW Asselbergs, C Willenborg, K Stirrups, L Folkersen, JR Thompson, S Kanoni, RJ Strawbridge, D Absher, T Meitinger, S Rafelt, A Dehghan
Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
Yanbo Fan, Michael Mathis, M Lin, HJ Cordell, EM Isselbacher, S Prakash, JB Nielsen, J Jiao, A Booher, L Folkersen, W Hornsby, Hyun Kang, EP Bottinger, A Franco-Cereceda, Lars Fritsche, C Schurmann, RJF Loos, Sachin Kheterpal, Chad Brummett, Cristen Willer, Jacob Kitzman, M Othman, Goncalo Abecasis, Bo Yang, L Farhat, SC Body, M Thomas, Yuqing Chen, Lin Chang, G Lettre, JA Goodship, MP Dubé, BD Keavney, P Eriksson, G Deeb, W Zhou, A Driscoll, GA Farnum, Alan Boyle, M Heydarpour, DC Guo, JC Tardif, A Levasseur, Santhi Ganesh, DM Milewicz, Kim Eagle
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
P Hoffmann, Trilokraj Tejasvi, A Metspalu, N Dand, HW Lim, Tsoi, S Weidinger, DA Hinds, S Das, C Tian, C Enerbäck, Johann Gudjonsson, GG Krueger, M Weichenthal, PE Stuart, T Esko, E Ellinghaus, DD Gladman, M Zawistowski, S Mucha, KC Duffin, John Voorhees, A Franke, R Trembath, U Mrowietz, V Chandran, A Reis, JN Barker, P Rahman, Rajan Nair, James Elder, S Kõks, N Eriksson, Hyun Kang, K Kingo, Xiaoquan Wen, Goncalo Abecasis
A reference panel of 64,976 haplotypes for genotype imputation
H Campbell, C Sidore, Y Luo, K Sharp, FS Collins, JC Barrett, A Angius, U Peters, RM Fraser, S Levy, H Zhang, D Melzer, C Fuchsberger, AE Farmaki, W Kretzschmar, P Danecek, M Dorr, E Chew, Michael Boehnke, S Gabriel, Laura Scott, D Boomsma, A Kwong, S McCarthy, M Mezzavilla, CM Van Duijn, KL Mohlke, Matthew Sampson, JL Min, Hyun Kang, Chad Brummett, Melvin McInnis, M Pato, Goncalo Abecasis, O Delaneau, GD Smith, M McGue, L Ferrucci, F Busonero, S Chen, JC Lee, Matthias Kretzler, L Groop, CE Gillies, A Chan, A Palotie, A Gilly, A Teumer, AR Wood, S Vrieze, T Harrison, OL Holmen, S Das, M Cocca, JB Vincent, LJ Corbin, Kari Branham, Cristen Willer, L Forer, A Hattersley, I Gandin, N Pirastu, A Mahajan, S Koskinen, M Nauck, J Veldink, G Dedoussis, G Breen, M Traglia, D Nickerson, K Hveem, T Meitinger, N Timpson
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
AU Jackson, Alan Weder, J Luan, E Boerwinkle, LP Lyytikäinen, N Bouatia-Naji, YJ Kim, GB Ehret, CY Cheng, AK Petersen, T Ferreira, S Kanoni, I Barroso, JC Bis, H Warren, EM Schmidt, M Burnier, LS Rallidis, LL Bonnycastle, D Baldassarre, D Absher, W Zhao, PS Chines, Cristen Willer, R Joehanes, IS Chang, R Jansen, LS Adair, M Bochud, B Balkau, DE Arking, T Axelsson, SK Kim, Michael Boehnke, L Lataniotis, LA Donnelly, N Eriksson, Hyun Kang, K Kristiansson, FS Collins, V Pihur, MR Barnes, S Shah, G Bjornsdottir, T Johnson, DI Boomsma, MJ Brown, DI Chasman, L Folkersen, MF Hughes, D Shungin, S Bevan, JC Chambers, Y Wu, TH Pers, S Bandinelli, AJP Smith, O Meirelles, ME Kleber, BO Tayo, N Amin, M Kaakinen, Santhi Ganesh, EL Salfati, E Theusch, IM Nolte, CP Cabrera, RJ Strawbridge, K Witkowska, G Thorleifsson, PK Magnusson, SR Bornstein, X Guo, C Fava, RH Chung, AD Johnson
The genetic architecture of type 2 diabetes
C Ma, P Fontanillas, M Van De Bunt, AG Day-Williams, X Wang, J Huang, V Agarwala, C Hartl, J Flannick, AE Locke, Y Nagai, CP Jenkinson, TW Blackwell, J Dupuis, T Ferreira, M Müller-Nurasyid, PS Chines, S Lee, NR Robertson, JF Tajes, D Pasko, J Yoon, Michael Boehnke, TJ Maxwell, YJ Kim, A Mahajan, MA Rivas, NL Beer, T Green, HM Stringham, P Cingolani, CM Lindgren, X Sim, T Kuulasmaa, KJ Gaulton, JE Below, Stephen Parker, N Grarup, L Moutsianas, T Fingerlin, DJ McCarthy, Y Kim, HM Highland, I Huh, M Horikoshi, RD Pearson, Hyun Kang, RA Scott, RP Welch, JR Huyghe, AU Jackson, MK Ikram, C Fuchsberger, TM Teslovich, H Chen, JRB Perry, A Kumar, NW Rayner, J Lee, ML Stitzel, MJ Go, ER Gamazon, W Zhang, Laura Scott, MS Kwon, P Chen, BG Han, C Hu, Goncalo Abecasis, KH Lin, BF Voight, TV Varga, N Barzilai, Y Chen
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture
P Hoffmann, HE Wichmann, GG Krueger, HW Lim, Tsoi, C Gieger, Yi Li, PJ Mease, Yun Li, S Das, EG Moreta, CT Ritchlin, Johann Gudjonsson, M Kunz, Trilokraj Tejasvi, PE Stuart, T Esko, E Ellinghaus, Robert Ike, DD Gladman, AM Bowcock, Hyun Kang, A Franke, S Weidinger, J Winkelmann, John Voorhees, U Mrowietz, K Kingo, MM Nöthen, V Chandran, K Callis-Duffin, C Enerbäck, PK Gregersen, Yanming Li, Rajan Nair, James Elder, S Kõks, P Rahman, Goncalo Abecasis, A Reis, Xiaoquan Wen, M Weichenthal
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
NW Rayner, JG Eriksson, RJ Strawbridge, E Eury, KJ Gaulton, DJ Couper, S Edkins, T Ferreira, NL Beer, SK Thomsen, H Grallert, G Thorleifsson, H Kestler, D Baldassarre, AT Crenshaw, G Charpentier, T Green, P Almgren, A Mahajan, R Mägi, C Ma, LL Bonnycastle, MC Cornelis, J Flannick, S Gustafsson, A Raimondo, PS Chines, C Fuchsberger, Y Lu, P Kwan, P Fontanillas, N Robertson, JK Rundle, EM Van Leeuwen, SM Willems, A Chalisey, V Steinthorsdottir, L Eisele, ME Reschen, L Qi, L Yengo, Laura Scott, EP Bottinger, Michael Boehnke, ASF Doney, D Thuillier, M Blüher, T Esko, S Wahl, M Linderman, NP Burtt, Hyun Kang, T Sparso, M Frånberg, M Van De Bunt, R Benediktsson, Goncalo Abecasis, I Prokopenko, M Dorkhan, H Chheda, A Locke, BF Voight, Y Lee, RA Scott, H Chen, B Balkau, H Boeing, M Li, RM Van Dam, J Carey, J Fadista, LC Karssen
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
Goncalo Abecasis, A Maschio, P Gasparini, R Lyons, D Toniolo, NJ Timpson, R Nagaraja, G Dedoussis, M Steri, Jennifer Bragg-Gresham, C Sidore, S Uzzau, D Schlessinger, CWK Chiang, R Atzeni, A Mulas, A Kwong, F Busonero, Hyun Kang, S Naitza, C Jones, C Fuchsberger, VDO Del Vecchyo, J Huang, R Berutti, M Pitzalis, G Malerba, E Zeggini, S Sanna, J Novembre, C Brennan, F Reinier, M Zoledziewska, N Soranzo, F Cucca, F Danjou, B Tarrier, E Porcu, G Pistis, A Angius
A global reference for human genetic variation
P Flicek, Y Li, D Muzny, N Gupta, DR Bentley, ME Hurles, BM Knoppers, RE Smith, Y Chang, A Thormann, W Zhang, GT Marth, N Gharani, H Doddapaneni, Y Zhu, I Streeter, Y Yin, R Wu, Hyun Kang, G Wang, GA McVean, JG Reid, DA Nickerson, V Korchina, G Kelman, RA Gibbs, X Fang, X Zheng, A Chakravarti, Y Lu, H Jiang, X Ma, M Jian, AG Clark, C Kovar, L Gil, E Kulesha, ED Green, L Clarke, R Leinonen, P Donnelly, ER Mardis, ES Lander, R Radhakrishnan, X Guo, X Liu, Y Han, RM Durbin, D Smirnov, M Zhao, JO Korbel, X Jin, Lars Fritsche, B Vaughan, S Lee, NP Gerry, ST Sherry, T Lan, SE Hunt, J Barker, WM McLaren, LH Toji, X Xu, C Lee, JP Schmidt, AM Resch, A Auton, H Lehrach, Jeffrey Kidd, M Tang, I Toneva, Ryan Mills, A Roa, E Boerwinkle, Goncalo Abecasis, Q Feng, DM Altshuler, SB Gabriel, RK Wilson, EE Eichler
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