Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
JB Nielsen, LG Fritsche, W Zhou, TM Teslovich, OL Holmen, S Gustafsson, ME Gabrielsen, EM Schmidt, R Beaumont, BN Wolford, M Lin, CM Brummett, MH Preuss, L Refsgaard, EP Bottinger, SE Graham, I Surakka, Y Chu, AH Skogholt, H Dalen, AP Boyle, H Oral, TJ Herron, J Kitzman, J Jalife, JH Svendsen, MS Olesen, I Njølstad, ML Løchen, A Baras, O Gottesman, A Marcketta, C O'Dushlaine, MD Ritchie, T Wilsgaard, RJF Loos, TM Frayling, M Boehnke, E Ingelsson, DJ Carey, FE Dewey, HM Kang, GR Abecasis, K Hveem, CJ Willer
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
J Flannick, C Fuchsberger, A Mahajan, TM Teslovich, V Agarwala, KJ Gaulton, L Caulkins, R Koesterer, C Ma, L Moutsianas, DJ McCarthy, MA Rivas, JRB Perry, X Sim, TW Blackwell, NR Robertson, NW Rayner, P Cingolani, AE Locke, JF Tajes, HM Highland, J Dupuis, PS Chines, CM Lindgren, C Hartl, AU Jackson, H Chen, JR Huyghe, M Van De Bunt, RD Pearson, A Kumar, M Müller-Nurasyid, N Grarup, HM Stringham, ER Gamazon, J Lee, Y Chen, RA Scott, JE Below, P Chen, J Huang, MJ Go, ML Stitzel, D Pasko, SCJ Parker, TV Varga, T Green, NL Beer, AG Day-Williams, T Ferreira, T Fingerlin, M Horikoshi, C Hu, I Huh, MK Ikram, BJ Kim, Y Kim, YJ Kim, MS Kwon, J Lee, S Lee, KH Lin, TJ Maxwell, Y Nagai, X Wang, RP Welch, J Yoon, W Zhang, N Barzilai, BF Voight, BG Han, CP Jenkinson, T Kuulasmaa, J Kuusisto
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data
SA Bien, PL Auer, TA Harrison, C Qu, CM Connolly, PG Greenside, S Chen, SI Berndt, S Bézieau, HM Kang, J Huyghe, H Brenner, G Casey, AT Chan, JL Hopper, BL Banbury, J Chang-Claude, SJ Chanock, RW Haile, M Hoffmeister, C Fuchsberger, MA Jenkins, SM Leal, M Lemire, PA Newcomb, S Gallinger, JD Potter, RE Schoen, ML Slattery, JD Smith, L Le Marchand, E White, BW Zanke, GR Abeçasis, CS Carlson, U Peters, DA Nickerson, A Kundaje, L Hsu
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk
I Brænne, L Zeng, C Willenborg, V Tragante, T Kessler, CJ Willer, M Laakso, L Wallentin, PW Franks, V Salomaa, A Dehghan, T Meitinger, NJ Samani, FW Asselbergs, J Erdmann, H Schunkert, P Deloukas, S Kanoni, M Farrall, TL Assimes, JR Thompson, E Ingelsson, D Saleheen, BA Goldstein, D Absher, IR König, K Stirrups, Å Johansson, AS Hall, JY Lee, JC Chambers, T Esko, L Folkersen, A Goel, E Grundberg, AS Havulinna, WK Ho, JC Hopewell, N Eriksson, ME Kleber, K Kristiansson, P Lundmark, LP Lyytikäinen, S Rafelt, D Shun, RJ Strawbridge
Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
B Yang, W Zhou, J Jiao, JB Nielsen, MR Mathis, M Heydarpour, G Lettre, L Folkersen, S Prakash, C Schurmann, L Fritsche, GA Farnum, M Lin, M Othman, W Hornsby, A Driscoll, A Levasseur, M Thomas, L Farhat, MP Dubé, EM Isselbacher, A Franco-Cereceda, DC Guo, EP Bottinger, GM Deeb, A Booher, S Kheterpal, YE Chen, HM Kang, J Kitzman, HJ Cordell, BD Keavney, JA Goodship, SK Ganesh, G Abecasis, KA Eagle, AP Boyle, RJF Loos, P Eriksson, JC Tardif, CM Brummett, DM Milewicz, SC Body, CJ Willer
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
LC Tsoi, PE Stuart, C Tian, JE Gudjonsson, S Das, M Zawistowski, E Ellinghaus, JN Barker, V Chandran, N Dand, KC Duffin, C Enerbäck, T Esko, A Franke, DD Gladman, P Hoffmann, K Kingo, S Kõks, GG Krueger, HW Lim, A Metspalu, U Mrowietz, S Mucha, P Rahman, A Reis, T Tejasvi, R Trembath, JJ Voorhees, S Weidinger, M Weichenthal, X Wen, N Eriksson, HM Kang, DA Hinds, RP Nair, GR Abecasis, JT Elder
A reference panel of 64,976 haplotypes for genotype imputation
S McCarthy, S Das, W Kretzschmar, O Delaneau, AR Wood, A Teumer, HM Kang, C Fuchsberger, P Danecek, K Sharp, Y Luo, C Sidore, A Kwong, N Timpson, S Koskinen, S Vrieze, LJ Scott, H Zhang, A Mahajan, J Veldink, U Peters, C Pato, CM Van Duijn, CE Gillies, I Gandin, M Mezzavilla, A Gilly, M Cocca, M Traglia, A Angius, JC Barrett, D Boomsma, K Branham, G Breen, CM Brummett, F Busonero, H Campbell, A Chan, S Chen, E Chew, FS Collins, LJ Corbin, GD Smith, G Dedoussis, M Dorr, AE Farmaki, L Ferrucci, L Forer, RM Fraser, S Gabriel, S Levy, L Groop, T Harrison, A Hattersley, OL Holmen, K Hveem, M Kretzler, JC Lee, M McGue, T Meitinger, D Melzer, JL Min, KL Mohlke, JB Vincent, M Nauck, D Nickerson, A Palotie, M Pato, N Pirastu, M McInnis
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
GB Ehret, T Ferreira, DI Chasman, AU Jackson, EM Schmidt, T Johnson, G Thorleifsson, J Luan, LA Donnelly, S Kanoni, AK Petersen, V Pihur, RJ Strawbridge, D Shungin, MF Hughes, O Meirelles, M Kaakinen, N Bouatia-Naji, K Kristiansson, S Shah, ME Kleber, X Guo, LP Lyytikäinen, C Fava, N Eriksson, IM Nolte, PK Magnusson, EL Salfati, LS Rallidis, E Theusch, AJP Smith, L Folkersen, K Witkowska, TH Pers, R Joehanes, SK Kim, L Lataniotis, R Jansen, AD Johnson, H Warren, YJ Kim, W Zhao, Y Wu, BO Tayo, M Bochud, D Absher, LS Adair, N Amin, DE Arking, T Axelsson, D Baldassarre, B Balkau, S Bandinelli, MR Barnes, I Barroso, S Bevan, JC Bis, G Bjornsdottir, M Boehnke, E Boerwinkle, LL Bonnycastle, DI Boomsma, SR Bornstein, MJ Brown, M Burnier, CP Cabrera, JC Chambers, IS Chang, CY Cheng, PS Chines, RH Chung, FS Collins
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, KJ Gaulton, C Ma, P Fontanillas, L Moutsianas, DJ McCarthy, MA Rivas, JRB Perry, X Sim, TW Blackwell, NR Robertson, NW Rayner, P Cingolani, AE Locke, JF Tajes, HM Highland, J Dupuis, PS Chines, CM Lindgren, C Hartl, AU Jackson, H Chen, JR Huyghe, M Van De Bunt, RD Pearson, A Kumar, M Müller-Nurasyid, N Grarup, HM Stringham, ER Gamazon, J Lee, Y Chen, RA Scott, JE Below, P Chen, J Huang, MJ Go, ML Stitzel, D Pasko, SCJ Parker, TV Varga, T Green, NL Beer, AG Day-Williams, T Ferreira, T Fingerlin, M Horikoshi, C Hu, I Huh, MK Ikram, BJ Kim, Y Kim, YJ Kim, MS Kwon, J Lee, S Lee, KH Lin, TJ Maxwell, Y Nagai, X Wang, RP Welch, J Yoon, W Zhang, N Barzilai, BF Voight, BG Han, CP Jenkinson, T Kuulasmaa
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, A Mahajan, A Locke, NW Rayner, N Robertson, RA Scott, I Prokopenko, LJ Scott, T Green, T Sparso, D Thuillier, L Yengo, H Grallert, S Wahl, M Frånberg, RJ Strawbridge, H Kestler, H Chheda, L Eisele, S Gustafsson, V Steinthorsdottir, G Thorleifsson, L Qi, LC Karssen, EM Van Leeuwen, SM Willems, M Li, H Chen, C Fuchsberger, P Kwan, C Ma, M Linderman, Y Lu, SK Thomsen, JK Rundle, NL Beer, M Van De Bunt, A Chalisey, HM Kang, BF Voight, GR Abecasis, P Almgren, D Baldassarre, B Balkau, R Benediktsson, M Blüher, H Boeing, LL Bonnycastle, EP Bottinger, NP Burtt, J Carey, G Charpentier, PS Chines, MC Cornelis, DJ Couper, AT Crenshaw, RM Van Dam, ASF Doney, M Dorkhan, S Edkins, JG Eriksson, T Esko, E Eury, J Fadista, J Flannick, P Fontanillas
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
C Sidore, F Busonero, A Maschio, E Porcu, S Naitza, M Zoledziewska, A Mulas, G Pistis, M Steri, F Danjou, A Kwong, VDO Del Vecchyo, CWK Chiang, J Bragg-Gresham, M Pitzalis, R Nagaraja, B Tarrier, C Brennan, S Uzzau, C Fuchsberger, R Atzeni, F Reinier, R Berutti, J Huang, NJ Timpson, D Toniolo, P Gasparini, G Malerba, G Dedoussis, E Zeggini, N Soranzo, C Jones, R Lyons, A Angius, HM Kang, J Novembre, S Sanna, D Schlessinger, F Cucca, GR Abecasis
A global reference for human genetic variation
A Auton, GR Abecasis, DM Altshuler, RM Durbin, DR Bentley, A Chakravarti, AG Clark, P Donnelly, EE Eichler, P Flicek, SB Gabriel, RA Gibbs, ED Green, ME Hurles, BM Knoppers, JO Korbel, ES Lander, C Lee, H Lehrach, ER Mardis, GT Marth, GA McVean, DA Nickerson, JP Schmidt, ST Sherry, J Wang, RK Wilson, E Boerwinkle, H Doddapaneni, Y Han, V Korchina, C Kovar, S Lee, D Muzny, JG Reid, Y Zhu, Y Chang, Q Feng, X Fang, X Guo, M Jian, H Jiang, X Jin, T Lan, G Li, J Li, Y Li, S Liu, X Liu, Y Lu, X Ma, M Tang, B Wang, G Wang, H Wu, R Wu, X Xu, Y Yin, D Zhang, W Zhang, J Zhao, M Zhao, X Zheng, N Gupta, N Gharani, LH Toji, NP Gerry, AM Resch, J Barker, L Clarke, L Gil, SE Hunt, G Kelman, E Kulesha, R Leinonen, WM McLaren, R Radhakrishnan, A Roa, D Smirnov, RE Smith, I Streeter, A Thormann, I Toneva, B Vaughan
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