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Evan Keller

Professor

MM Urology

Orcid identifier0000-0002-7592-7535
  • Professor
    MM Urology
  • Center Member
    Center for Computational Medicine and Bioinformatics
  • Professor
    MM Pathology
  • Center Member
    Rogel Cancer Center
  • Center Member
    Global REACH
  • Associate Professor
    MM Unit for Laboratory Animal Medicine
  • Center Member
    Caswell Diabetes Institute
  • Center Member
    Biointerfaces Institute
  • Center Member
    Precision Health Initiative

BIO

Evan T. Keller, DVM, PhD is a Professor of Urology and Pathology, School of Medicine, University of Michigan. He is Director of the Single Cell Spatial Analysis Program; Associate Director for Shared Resource for the University of Michigan Comprehensive Rogel Cancer Center; Directs an NIH-funded Program Project on Prostate Cancer Bone Metastasis; and Co-Director of the Single Cell Analysis Core. Dr. Keller obtained Doctor of Veterinary Medicine (DVM) and Master of Preventive Veterinary Medicine (MPVM) degrees at University of California and attained American College of Veterinary Internal Medicine certification in Oncology and a PhD in Developmental Biology at the University of Wisconsin, Madison. His areas of research include (1) prostate cancer metastasis research, with a special emphasis on bone metastasis and the tumor microenvironment and (2) single cell and spatial analytic methods. Key research accomplishments include (1) defining importance of osteoclastic activity and targeting it in prostate cancer leading to clinical use of RANKL inhibitor (Denosumab); (2) identification of raf kinase inhibitor protein (RKIP) as a novel metastasis suppressor gene; (3) determining the importance of the Wnt pathway in bone metastasis; and (4) defining interleukin-6 as a contributor to castration resistant prostate cancer.

UNIVERSITY OF MICHIGAN APPOINTMENTS

  • Professor
    MM Urology
  • Center Member
    Center for Computational Medicine and Bioinformatics
  • Professor
    MM Pathology
  • Center Member
    Rogel Cancer Center
  • Center Member
    Global REACH
  • Associate Professor
    MM Unit for Laboratory Animal Medicine
  • Center Member
    Caswell Diabetes Institute
  • Center Member
    Biointerfaces Institute
  • Center Member
    Precision Health Initiative

DEGREES

  • DVM
    University of California, Davis, United States
  • MPVM
    University of California, Davis, Ann Arbor, United States
  • PhD
    University of Wisconsin, Madison, United States

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